Add to ORKGObjective ABCC8 mutations cause neonatal diabetes that can be transient (TNDM) or less commonly permanent (PNDM); ~90% individuals can be treated with oral sulfonylureas instead of insulin. Previous studies suggested that people with ABCC8-PNDM require lower sulfonylurea doses and have milder neurological features than those with KCNJ11-PNDM. However, these studies were short-term and included combinations of permanent and transient forms of ABCC8-NDM. We aimed to assess the long-term glycemic and neurological outcomes in sulfonylurea-treated ABCC8-PNDM. Research Design and Methods We studied all 24 individuals with ABCC8-PNDM diagnosed in the UK, Italy, France or USA known to transfer from insulin to sulfonylureas before May 2010...
Neonatal diabetes mellitus (NDM) is a rare genetic disease characterized by severe hyperglycemia req...
Permanent neonatal diabetes mellitus is most commonly caused by mutations in the ATP-sensitive potas...
Permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and p...
Objective ABCC8 mutations cause neonatal diabetes that can be transient (TNDM) or less commonly pe...
Objective: ABCC8 mutations cause neonatal diabetes mellitus that can be transient (TNDM) or, less co...
Background KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive potas...
Background. KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive pota...
Background: KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive pota...
BACKGROUND: Neonatal diabetes mellitus (NDM) is a rare but important condition affecting approximate...
Aims/hypothesis Activating mutations in the KCNJ11 gene encoding the Kir6.2 subunit of the K-ATP cha...
Permanent neonatal diabetes mellitus (PNDM) is a rare condition presenting before six months of age....
Background: Permanent neonatal diabetes caused by mutations in the KCNJ11 gene may be managed with h...
Neonatal diabetes mellitus (NDM) is a rare genetic disease characterized by severe hyperglycemia req...
Permanent neonatal diabetes mellitus is most commonly caused by mutations in the ATP-sensitive potas...
Permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and p...
Objective ABCC8 mutations cause neonatal diabetes that can be transient (TNDM) or less commonly pe...
Objective: ABCC8 mutations cause neonatal diabetes mellitus that can be transient (TNDM) or, less co...
Background KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive potas...
Background. KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive pota...
Background: KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive pota...
BACKGROUND: Neonatal diabetes mellitus (NDM) is a rare but important condition affecting approximate...
Aims/hypothesis Activating mutations in the KCNJ11 gene encoding the Kir6.2 subunit of the K-ATP cha...
Permanent neonatal diabetes mellitus (PNDM) is a rare condition presenting before six months of age....
Background: Permanent neonatal diabetes caused by mutations in the KCNJ11 gene may be managed with h...
Neonatal diabetes mellitus (NDM) is a rare genetic disease characterized by severe hyperglycemia req...
Permanent neonatal diabetes mellitus is most commonly caused by mutations in the ATP-sensitive potas...
Permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and p...