The True Utility of Predictive Models Based on Magnetic Resonance Imaging in Selecting Candidates for Prostate Biopsy

Early detection of clinically significant prostate cancer (csPCa) has improved since the introduction of magnetic resonance imaging (MRI) and guided biopsies for this purpose; however, suspicion of PCa is still based on elevated serum prostate-specific antigen and/or abnormal digital rectal examination. At present, the decision to perform a prostate biopsy primarily depends on the Prostate Imaging-Reporting and Data System (PI-RADS) score for lesions observed on MRI. Prostate biopsy is typically avoided when negative MRI (PI-RADS