Despite the availability of vaccines and antiviral medication, SARS-CoV-2 still presents a significant threat to public health. New variants of SARS-CoV-2 continue to emerge. As a result, the need to develop and evaluate new vaccinations strategies is critical. In this thesis the S1 region (amino acid residues 14Q-685R) containing the receptor binding domain of the SARS-CoV-2 spike protein was fused to the Fc region of IgG2a mouse antibody. A polymerase chain reaction was done to amplify the segment of interest, in parallel to the digestion of the vector pFUSE-mIgG2a-Fc2. The experimental cloning was done by ligating the two segments together. To express and purify SARS-CoV-2 S1 14Q-685R/pFUSE, Chinese hamster ovaries cells were transfected...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to coronavirus disease 2019 (COVID-...
Despite the availability of vaccines and antiviral medication, SARS-CoV-2 still presents a significa...
Coronaviruses are a significant threat to human health. In the last two decades there have been SARS...
[[abstract]]The spike (S) glycoprotein is thought to play a complex and central role in the biology ...
ABSTRACT The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been ...
AbstractThe spike (S) protein of SARS coronavirus (SARS-CoV) is responsible for viral binding with A...
The Spike (S) protein of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) pla...
The immunological characteristics of SARS-CoV spike protein were investigated by administering mice ...
The spike (S) protein of SARS coronavirus (SARS-CoV) is responsible for viral binding with ACE2 mole...
The outbreak of severe acute respiratory syndrome (SARS), caused by a distinct coronavirus, in 2003 ...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to coronavirus disease 2019 (COVID-...
In the face of the worldwide threat of severe acute respiratory syndrome (SARS) to human life, some ...
In 2020 the world faced the pandemic of COVID‐19 severe acute respiratory syndrome caused by a new t...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to coronavirus disease 2019 (COVID-...
Despite the availability of vaccines and antiviral medication, SARS-CoV-2 still presents a significa...
Coronaviruses are a significant threat to human health. In the last two decades there have been SARS...
[[abstract]]The spike (S) glycoprotein is thought to play a complex and central role in the biology ...
ABSTRACT The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been ...
AbstractThe spike (S) protein of SARS coronavirus (SARS-CoV) is responsible for viral binding with A...
The Spike (S) protein of the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) pla...
The immunological characteristics of SARS-CoV spike protein were investigated by administering mice ...
The spike (S) protein of SARS coronavirus (SARS-CoV) is responsible for viral binding with ACE2 mole...
The outbreak of severe acute respiratory syndrome (SARS), caused by a distinct coronavirus, in 2003 ...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to coronavirus disease 2019 (COVID-...
In the face of the worldwide threat of severe acute respiratory syndrome (SARS) to human life, some ...
In 2020 the world faced the pandemic of COVID‐19 severe acute respiratory syndrome caused by a new t...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the Coronavirus...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) led to coronavirus disease 2019 (COVID-...