Akralni melanom – prikaz 122 slučaja

The study includes 122 patients with acral melanoma (about 9.2% of all 1325 melanoma patients treated in the University Hospital for Tumors, Zagreb, Croatia from 1975 to 2002). Of them, there were 76 (62.3%) female and 46 (37.7%) male patients, with a mean age of 58 years. In 88 (72.1%) of the cases, the tumor was located on the legs and 34 (27.9%) of the patients had the tumor on the hands, of whom 15 (12.3%) under the nail plate. In the majority of cases, surgical treatment included wide excision of primary tumor and plastic reconstruction, or amputation in case of subungual melanoma. Dissection of clinically confirmed metastases in regional lymph nodes and sentinel node biopsy were performed in 35 (28.7%) and 2 (1.6%) of the patients, respectively. The five-year survival rate was 50% in stage I and II and 20% in stage III patients.U radu su analizirana 122 bolesnika s akralnim melanomom ili oko 9,2% od 1.325 ukupno liječenih u Klinici za tumore u Zagrebu, od 1975 do 2002. Liječeno je 76 (62,3%) žena i 46 (37,7%) muškaraca prosječne dobi 58 godina. U 88 (72,1%) bolesnika tumor je bio na nogama, u 34 (27,9%) bolesnika na rukama, a među njima bilo je 15 (12,3%) ispod noktiju. Kirurško liječenje najčešće je uključivalo široku eksciziju primarnog tumora i plastiku, a kod melanoma ispod noktiju, amputaciju. U 35 (28,7%) bolesnika učinjena je disekcija klinički dokazanih metastaza u regionalnim limfnim čvorovima, a u 2 (1,6%) bolesnika učinjena je biospija sentinel čvora. Petogodišnje preživljenje u bolesnika stadija I i II bilo je 50%, a u stadiju III 20%