Suportivno liječenje bolesnika s karcinomom

Malnutrition is a common problem among cancer patients. Cachexia causes death in >20% of patients with malignancy. Cachexia is most pronounced in patients with carcinoma of the stomach and pancreas. The aim of the study was to see whether appetite can be increased and weight loss decelerated using the pharmacological approach to appetite stimulation. The study is retrospective and relates to 20 patients with cancer of different localization treated over a two-month period. The patients received individual dietary recommendations, nutrition support and megestrol acetate 400mg/day. All patients were assessed by using the PG – SGA score (Patient Generated Subjective Global Assessment) and ECOG status. Throughout the two-month period, appetite changes using a visual analogue scale and body wieght changes were measured every two weeks. With nutritional advice and pharmacological support, the appetite significantly increased to reach the appetite score – good (p20% oboljelih od malignih bolesti. Kaheksija je najizraženija u bolesnika s karcinomom želuca i gušterače. Cilj rada bio je utvrditi je li moguće povećati apetit i usporiti gubitak tjelesne težine farmakološkim liječenjem stimulatorom apetita. Retrospektivno smo obradili dvomjesečno razdoblje u kojem smo liječili 20 bolesnika oboljelih od karcinoma različite lokalizacije. Bolesnici su pojedinačno dobili prehrambene savjete, nutritivnu potporu i megestrol-acetat 400mg/dan. Bolesnicima smo odredili PG – SGA skor (Patient Generated Subjective Global Assessment) i ECOG status. Tijekom dvomjesečnog razdoblja pratili smo svaka dva tjedna promjene apetita bolesnika koristeći se vizualno analognom skalom i promjenama u tjelesnoj težini. Nutritivnim savjetima i framakološkom potporom apetit se znatno poboljšao u 75% bolesnika do kategorije dobrog apetita (p