Clinical variables associated with failure of retinal detachment repair: the European vitreo-retinal society retinal detachment study report number 4

Objective: To identify risk factors associated with failure of anatomic reattachment in primary rhegmatogenous retinal detachment repair.Design: Nonrandomized, multicenter, collaborative study.Participants: Primary procedures for 7678 rhegmatogenous retinal detachments reported by 176 surgeons from 48 countries.Methods: We recorded specific preoperative clinical findings, repair method, and outcome after intervention. We performed univariate, bivariate, and multivariate analyses to identify variables associated with surgical failure.Main outcome measures: Final failure of retinal detachment repair (level 1), remaining silicone oil at study conclusion (level 2), and need for additional procedures to repair the detachment (level 3).Results: We analyzed 7678 cases of rhegmatogenous retinal detachment repair. Presence of choroidal detachment or significant hypotony was associated with significantly higher level 1 failure rates when grade 0 or B proliferative vitreoretinopathy (PVR) was present and higher level 2 failure rates, regardless of PVR status (P