Synthesis, characterization, and preliminary chemosensory ability of a novel 2,4,5-Tri(Hetero)Arylimidazole based on an 8-Hydroxy-Quinoline group

2,4,5-Trisubstituted imidazole derivatives with heteroaromatic groups are versatile heterocyclic compounds exhibiting a wide range of biological activities, as well as very interesting thermal, optical, electronic, and redox properties. In recent years, this type of imidazole derivatives has been explored as colorimetric and fluorimetric chemosensors due to their ability to coordinate with ions of biological and environmental relevance. In order to continue the work developed by the research group, we report the synthesis and characterization using usual spectroscopic techniques (NMR, absorption and emission spectroscopies) of a new imidazole derivative, sub-stituted at position 2 of the imidazole with an 8-hydroxy-quinoline group. Furthermore, to com-plement the characterization of the synthesized imidazole, a preliminary study as an optical chemosensor was carried out in acetonitrile in the presence of ions with biological, medicinal, and environmental relevance.This research was funded by the Foundation for Science and Technology (FCT) for financial support to CQ/UM (UID/QUI/00686/2020). Thanks are also due to FCT for financial support to the Portuguese NMR Network (PTNMR, Bruker Avance III 400-Univ. Minho)