Collagen Hydrogels Loaded with Silver Nanoparticles and Cannabis Sativa Oil
- Antezana, Pablo Edmundo
- Municoy, Sofia
- Pérez, Claudio Javier
- Desimone, Martín Federico
DOIAbstract
Wounds represent a major healthcare problem especially in hospital-associated infections where multi-drug resistant strains are often involved. Nowadays, biomaterials with therapeutic molecules play an active role in wound healing and infection prevention. In this work, the development of collagen hydrogels loaded with silver nanoparticles and Cannabis sativa oil extract is described. The presence of the silver nanoparticles gives interesting feature to the biomaterial such as improved mechanical properties or resistance to collagenase degradation but most important is the long-lasting antimicrobial effect. Cannabis sativa oil, which is known for its anti-inflammatory and analgesic effects, possesses antioxidant activity and successfully im...
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