Add to ORKGMonepantel (MNP) is a novel anthelmintic drug with a distinctive mode of action. MNP is active against a variety of multidrug resistant gastrointestinal (GI) nematodes. The characterization of the concentration profiles atteined at specific GI sites of parasite location and the establishment of the relationship between their plasma and gastrointestinal content/tissues availabilities is relevant. Also, the comparative metabolic stability in this organ is necessary when novel compounds are launched for enteral administration in rumiants. The pharmacological interactions obtained after the concomitant administration of MNP with other anthelmintics were also evaluated. The current review described an integrated pharmacological assessment of MNP...
Objective: To determine the efficacy of monepantel, a developmental compound from the amino-acetonit...
The search for novel alternatives to control gastrointestinal nematodes in ruminants is relevant con...
Anthelmintic drugs require effective concentrations to be attained at the site of parasite location ...
Monepantel (MNP) is a novel amino-acetonitrile derivative anthelmintic drug. Based on a distinctive ...
The amino-acetonitrile derivatives (AADs) are a new class of anthelmintic molecules active against a...
The increasing levels of resistance to all traditional anthelmintic classes have encouraged the sear...
The work described here complements previous findings on monepantel (MNP) pharmacological behaviour ...
Monepantel (MNP) is a new amino-acetonitrile derivative anthelmintic drug used for the treatment of ...
The correct use of pharmacology-based information is critical to design successful strategies for th...
The concurrent administration of drugs is currently used in veterinary medicine. In cattle, the coad...
Monepantel (MNP) is a novel anthelmintic compound launched into the veterinary pharmaceutical market...
The search of novel strategies to control gastrointestinal nematodes in ruminants is a concern consi...
AIMS: To compare the pharmacokinetics, distribution and efficacy (pharmacodynamic response) of intra...
In a context of nematodicidal resistance, anthelmintic combinations have emerged as a reliable pharm...
In a context of increasing anthelmintic resistance, combination of synthetic anthelmintics with bioa...
Objective: To determine the efficacy of monepantel, a developmental compound from the amino-acetonit...
The search for novel alternatives to control gastrointestinal nematodes in ruminants is relevant con...
Anthelmintic drugs require effective concentrations to be attained at the site of parasite location ...
Monepantel (MNP) is a novel amino-acetonitrile derivative anthelmintic drug. Based on a distinctive ...
The amino-acetonitrile derivatives (AADs) are a new class of anthelmintic molecules active against a...
The increasing levels of resistance to all traditional anthelmintic classes have encouraged the sear...
The work described here complements previous findings on monepantel (MNP) pharmacological behaviour ...
Monepantel (MNP) is a new amino-acetonitrile derivative anthelmintic drug used for the treatment of ...
The correct use of pharmacology-based information is critical to design successful strategies for th...
The concurrent administration of drugs is currently used in veterinary medicine. In cattle, the coad...
Monepantel (MNP) is a novel anthelmintic compound launched into the veterinary pharmaceutical market...
The search of novel strategies to control gastrointestinal nematodes in ruminants is a concern consi...
AIMS: To compare the pharmacokinetics, distribution and efficacy (pharmacodynamic response) of intra...
In a context of nematodicidal resistance, anthelmintic combinations have emerged as a reliable pharm...
In a context of increasing anthelmintic resistance, combination of synthetic anthelmintics with bioa...
Objective: To determine the efficacy of monepantel, a developmental compound from the amino-acetonit...
The search for novel alternatives to control gastrointestinal nematodes in ruminants is relevant con...
Anthelmintic drugs require effective concentrations to be attained at the site of parasite location ...