Colorectal cancer (CRC) is one of the most commonly occurring cancers worldwide. Although several genetic alterations have been associated with CRC onset and progression, nowadays the reprogramming of cellular metabolism has been recognized as a fundamental step of the carcinogenic process. Intestinal tumor cells frequently display an aberrant activation of lipid metabolism. Indeed, to satisfy the growing needs of a continuous proliferation, cancer cells can either increase the uptake of exogenous lipids or upregulate the endogenous lipogenesis and cholesterol synthesis. Therefore, strategies aimed at limiting lipid accumulation are now under development in order to counteract malignancies. Two major players of lipids metabolism have been s...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Liver X receptors (LXRs) are members of the nuclear receptor superfamily of DNA-binding transcriptio...
Liver X receptors (LXRs) are members of the nuclear receptor superfamily of DNA-binding transcriptio...
Colorectal cancer (CRC) is one of the most commonly occurring cancers worldwide. Although several ge...
Cancer cells frequently display specific alterations in their metabolic activity. Reprogramming of l...
[[abstract]]Liver X receptors (LXRalpha and LXRbeta) are members of the nuclear receptor family and ...
BACKGROUND & AIMS: Liver X receptors (LXRs) are transcriptional regulators of cholesterol metabolism...
Abstract Background Accumulating evidence indicates alterations in lipid metabolism and lipid compos...
Resumen del póster presentado al 2nd Symposium on Biomedical Research: "Advances and perspectives in...
Le métabolisme de la cellule cancéreuse s’adapte aux besoins en macromolécules de cette cellule en p...
Abstract Altered metabolism of lipids is currently considered a hallmark characteristic of many mali...
Lipids have diverse structures, with multifarious regulatory functions in membrane homeostasis and b...
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths. Understanding its path...
Human colorectal cancer is the progressive accumulation of mutations that occur in the epithelial li...
Background: The expansion and metastasis of colorectal cancers are closely associated with the dynam...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Liver X receptors (LXRs) are members of the nuclear receptor superfamily of DNA-binding transcriptio...
Liver X receptors (LXRs) are members of the nuclear receptor superfamily of DNA-binding transcriptio...
Colorectal cancer (CRC) is one of the most commonly occurring cancers worldwide. Although several ge...
Cancer cells frequently display specific alterations in their metabolic activity. Reprogramming of l...
[[abstract]]Liver X receptors (LXRalpha and LXRbeta) are members of the nuclear receptor family and ...
BACKGROUND & AIMS: Liver X receptors (LXRs) are transcriptional regulators of cholesterol metabolism...
Abstract Background Accumulating evidence indicates alterations in lipid metabolism and lipid compos...
Resumen del póster presentado al 2nd Symposium on Biomedical Research: "Advances and perspectives in...
Le métabolisme de la cellule cancéreuse s’adapte aux besoins en macromolécules de cette cellule en p...
Abstract Altered metabolism of lipids is currently considered a hallmark characteristic of many mali...
Lipids have diverse structures, with multifarious regulatory functions in membrane homeostasis and b...
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths. Understanding its path...
Human colorectal cancer is the progressive accumulation of mutations that occur in the epithelial li...
Background: The expansion and metastasis of colorectal cancers are closely associated with the dynam...
This is an open-access article distributed under the terms of the Creative Commons Attribution Licen...
Liver X receptors (LXRs) are members of the nuclear receptor superfamily of DNA-binding transcriptio...
Liver X receptors (LXRs) are members of the nuclear receptor superfamily of DNA-binding transcriptio...