Diagnostic Value of the Early Heart-to-Mediastinum Count Ratio in Cardiac 123I-mIBG imaging for Parkinson's Disease
- Frantellizzi, Viviana
- Lavelli, Valentina
- Ferrari, Cristina
- Sardaro, Angela
- Farcomeni, Alessio
- Pacilio, Massimiliano
- Borrazzo, Cristian
- Pani, Roberto
- Rubini, Giuseppe
- Vincentis, Giuseppe De
Publication date
January 2020
DOI Publisher
Bentham Science Publishers Ltd. Language
EnglishAbstract
Early diagnosis of Parkinson's disease (PD) is of primary importance. The delayed (3-4 h after injection) Iodine-123-Metaiodobenzylguanidine (123I-mIBG) scintigraphy has been proven to be effective in early differential diagnosis for Lewy body disease. But early imaging (15-30 min after injection) has only been marginally studied for its possible diagnostic role. In this prospective study a thresholdfor the early Heart-to-Mediastinum (H/M) count ratio has been investigated, obtaining a diagnostic accuracy analogous to conventional, delayed imaging
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