A series of dihetero[8]helicenes have been systematically synthesized in enantiomerically enriched forms by utilizing the characteristic transformations of the organosulfur functionality. The synthetic route begins with assembling a ternaphthyl common synthetic intermediate from 2-naphthol and bissulfinylnaphthalene through an extended Pummerer reaction followed by facile multi-gram-scale resolution. The subsequent cyclization reactions into dioxa- and dithia[8]helicenes take place with excellent axial-to-helical chirality conversion. Dithia[8]helicene is further transformed into the nitrogen and the carbon analogs by replacing the two endocyclic sulfur atoms via SNAr-based skeletal reconstruction. The efficient systematic synthesis has ena...
Enantiopure tris-helicenic chiral-at-iridium complexes have been prepared, constituting the first ex...
Helicenes are ortho-condensed polycyclic aromatic or heteroaromatic compounds with inherent chiralit...
Hetero[8]circulenes are an interesting class of polycyclic heteroaromatic molecules having rigid and...
Four members of a new class of cycloborylated hexa-, octa-, and deca-helicenes (1 a–d) have been pre...
京都大学新制・課程博士博士(薬科学)甲第23386号薬科博第143号新制||薬科||16(附属図書館)京都大学大学院薬学研究科薬科学専攻(主査)教授 川端 猛夫, 教授 高須 清誠, 教授 大野 浩章...
The golden twist: Monodentate [5]helicene-imidazolylidene gold(I) complexes were prepared in good yi...
Helicenes are ortho-condensed polycyclic aromatic or heteroaromatic compounds with inherent chiralit...
Helicenes, as part of the larger family of helical shaped small molecules, are not only original, a...
Helicenes are inherently chiral polycyclic aromatic molecules. Laterally extended helicenes have the...
International audienceElectroactive fused ethylenedithio-tetrathiafulvalene-[4]helicene and -[6]heli...
The synthesis of a second-generation [6]-helicenoidal DMAP organocatalyst is reported. The synthesis...
Shagene AおよびBの化学合成 --リーシュマニア症の治療薬リードの創製を目指して--. 京都大学プレスリリース. 2021-09-10.We report the first total sy...
We have carried out the synthesis of two dithia[9]helicenes by means of a LED-based double photocycl...
Schinortriterpenoids, such as pre-schisanartanin A and arisanlactone C, are complex and highly oxyge...
International audienceHelicenes are fascinating molecules owing to their unusual properties and appl...
Enantiopure tris-helicenic chiral-at-iridium complexes have been prepared, constituting the first ex...
Helicenes are ortho-condensed polycyclic aromatic or heteroaromatic compounds with inherent chiralit...
Hetero[8]circulenes are an interesting class of polycyclic heteroaromatic molecules having rigid and...
Four members of a new class of cycloborylated hexa-, octa-, and deca-helicenes (1 a–d) have been pre...
京都大学新制・課程博士博士(薬科学)甲第23386号薬科博第143号新制||薬科||16(附属図書館)京都大学大学院薬学研究科薬科学専攻(主査)教授 川端 猛夫, 教授 高須 清誠, 教授 大野 浩章...
The golden twist: Monodentate [5]helicene-imidazolylidene gold(I) complexes were prepared in good yi...
Helicenes are ortho-condensed polycyclic aromatic or heteroaromatic compounds with inherent chiralit...
Helicenes, as part of the larger family of helical shaped small molecules, are not only original, a...
Helicenes are inherently chiral polycyclic aromatic molecules. Laterally extended helicenes have the...
International audienceElectroactive fused ethylenedithio-tetrathiafulvalene-[4]helicene and -[6]heli...
The synthesis of a second-generation [6]-helicenoidal DMAP organocatalyst is reported. The synthesis...
Shagene AおよびBの化学合成 --リーシュマニア症の治療薬リードの創製を目指して--. 京都大学プレスリリース. 2021-09-10.We report the first total sy...
We have carried out the synthesis of two dithia[9]helicenes by means of a LED-based double photocycl...
Schinortriterpenoids, such as pre-schisanartanin A and arisanlactone C, are complex and highly oxyge...
International audienceHelicenes are fascinating molecules owing to their unusual properties and appl...
Enantiopure tris-helicenic chiral-at-iridium complexes have been prepared, constituting the first ex...
Helicenes are ortho-condensed polycyclic aromatic or heteroaromatic compounds with inherent chiralit...
Hetero[8]circulenes are an interesting class of polycyclic heteroaromatic molecules having rigid and...