Synthesis of selagibenzophenone C and derivatives for confirmation of the stucture of the natural product.

5 Abstract This bachelor's thesis deals with the preparation of selagibenzophenone C. The natural product was prepared in a six-step synthesis, where subsequent analysis and comparison of the spectrum of the synthetic substance with the spectra described for the isolated product verified whether the structure of the isolated natural product was deciphered correctly. Furthermore, it was verified that intermediates in the synthesis of selagibenzophenone C can undergo cyclization reactions to form a fluorene core. Analogous cyclization is the main step in the biosynthesis of selaginpulvilins from the corresponding selaginellins. The obtained fluorene derivatives will therefore be used as standards in the following studies to determine whether these substances obtained by us are also natural compounds. Key words Total synthesis, natural product, polyphenols, natural fluorene derivates, selagibenzophenone