Add to ORKGUsing data obtained from a pilot study, Browne (1995) proposed a procedure for estimating the sample size needed for a definitive two-arm randomised controlled trial when the minimal important difference is specified. Simulations confirm these findings. The results attributable to Browne are extended to consider the degree of error attached to sample size estimation using this procedure. A consideration of the error provides a simple mechanism to estimate the sample size needed for a pilot study so as to control the degree of error in the follow-on substantive trial
Researchers routinely compute desired sample sizes of clinical trials to control type-i and type-ii ...
The determination of the appropriate sample size is an important aspect of planning a clinical trial...
Estimation of sample size in clinical trials requires knowledge of parameters that involve the treat...
Using data obtained from a pilot study, Browne (1995) proposed a procedure for estimating the sample...
In practice, the required sample size for a two-arm randomised controlled trial cannot always be det...
In the two sample binomial case, one approach to the estimation of sample size is to conduct a pilot...
BackgroundExternal pilot or feasibility studies can be used to estimate key unknown parameters to in...
One of the goals of a pilot study is to identify unforeseen problems, such as ambiguous inclusion or...
Sample size justification is an important consideration when planning a clinical trial, not only for...
BACKGROUND: In conducting randomized trials, formal estimations of sample size are required to ensur...
We discuss different methods of sample size calculation for two independent means, aiming to provide...
Estimating population effect size accurately and precisely plays a vital role in achieving a desired...
When designing a clinical trial an appropriate justification for the sample size should be provided ...
An essential part of any medical research is to decide how many subjects need to be studied. A forma...
In many casses the estimation of variance which is used to determine sample size in clinical trials,...
Researchers routinely compute desired sample sizes of clinical trials to control type-i and type-ii ...
The determination of the appropriate sample size is an important aspect of planning a clinical trial...
Estimation of sample size in clinical trials requires knowledge of parameters that involve the treat...
Using data obtained from a pilot study, Browne (1995) proposed a procedure for estimating the sample...
In practice, the required sample size for a two-arm randomised controlled trial cannot always be det...
In the two sample binomial case, one approach to the estimation of sample size is to conduct a pilot...
BackgroundExternal pilot or feasibility studies can be used to estimate key unknown parameters to in...
One of the goals of a pilot study is to identify unforeseen problems, such as ambiguous inclusion or...
Sample size justification is an important consideration when planning a clinical trial, not only for...
BACKGROUND: In conducting randomized trials, formal estimations of sample size are required to ensur...
We discuss different methods of sample size calculation for two independent means, aiming to provide...
Estimating population effect size accurately and precisely plays a vital role in achieving a desired...
When designing a clinical trial an appropriate justification for the sample size should be provided ...
An essential part of any medical research is to decide how many subjects need to be studied. A forma...
In many casses the estimation of variance which is used to determine sample size in clinical trials,...
Researchers routinely compute desired sample sizes of clinical trials to control type-i and type-ii ...
The determination of the appropriate sample size is an important aspect of planning a clinical trial...
Estimation of sample size in clinical trials requires knowledge of parameters that involve the treat...