Bovine leucocyte adhesion deficiency [BLAD] and its worldwide prevalence

Bovine leukocyte adhesion deficiency (BLAD) is a well characterised lethal autosomal recessive disease that occurs in Holstein cattle. The discovery of this genetic disorder in 1990 by KEHRLI et al. was serendipitous and occurred in conjunction with studies of new methods to prevent mastitis in periparturient dairy cows ( KEHRLI et al. 1992a). In this review article we are attempting to summarise the last 6-year research (1990-1995) covering major aspects of BLAD syndrome, its worldwide prevalence with emphasize on current and future development on BLAD research