High-Frequency Ultrasound-Guided Injection for the Generation of a Novel Orthotopic Mouse Model of Human Thyroid Carcinoma
- Greco, Adelaide
- Albanese, Sandra
- Auletta, Luigi
- Mirabelli, Peppino
- Zannetti, Antonella
- D'Alterio, Crescenzo
- Di Maro, Gennaro
- Orlandella, Francesca Maria
- Salvatore, Giuliana
- Soricelli, Andrea
- Salvatore, Marco
Publication date
January 2016
DOI Publisher
Mary Ann Liebert Inc ISSN
1050-7256 Citation count (estimate)
2Abstract
Thyroid carcinoma is the most common endocrine malignancy and has an increasing incidence. High-frequency ultrasound (HFUS) has a spatial resolution of 30 μm, which is a property that has been exploited for thyroid visualization and analysis in mice. The aim of this study was to generate a novel orthotopic mouse model of human follicular thyroid carcinoma (FTC) using an HFUS-guided injection system
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