International audienceAzole resistant Aspergillus fumigatus strains are increasingly reported in many countries. One resistance mechanism is attributed to the use of azole fungicides in environment. Two mutations, TR34/L98H and TR46/Y121F/T289A, on the cyp51A gene, have been described. Results of 40 publications about azole resistant strain detections, with TR34/L98H and TR46/Y121F/T289A mutations, in clinical and/or environmental samples, are presented in this review. These cases, observed in many countries, suggest spreading phenomenon. Measures to moderate fungicides treatments and/or alternative treatments in environment should be established to preserve the effectiveness of azole antifungal therapy for at-risk patients
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Azole resistance is an emerging problem in Aspergillus which impacts the management of aspergillosis...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Aspergillus fumigatus is a ubiquitous opportunistic pathogen. This fungus can acquire resistance to ...
Invasive aspergillosis due to multi-azole-resistant Aspergillus fumigatus has emerged in the Netherl...
Aspergillus fumigatus is a ubiquitous opportunistic pathogen. This fungus can acquire resistance to ...
Aspergillus fumigatus is a ubiquitous opportunistic pathogen. This fungus can acquire resistance to ...
Azole antifungal resistance in Aspergillus fumigatus is a worldwide concern. As in most public hospi...
Azole-resistance in Aspergillus fumigatus is emerging and is becoming an increasing problem in the m...
Azole resistance in Aspergillus is emerging in European and Asian countries. As azoles are mainstay ...
Azole resistance in Aspergillus is emerging in European and Asian countries. As azoles are mainstay ...
Azole resistance in Aspergillus has emerged as an escalating problem in health care, and it has been...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Azole resistance in Aspergillus has emerged as an escalating problem in health care, and it has been...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Azole resistance is an emerging problem in Aspergillus which impacts the management of aspergillosis...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Aspergillus fumigatus is a ubiquitous opportunistic pathogen. This fungus can acquire resistance to ...
Invasive aspergillosis due to multi-azole-resistant Aspergillus fumigatus has emerged in the Netherl...
Aspergillus fumigatus is a ubiquitous opportunistic pathogen. This fungus can acquire resistance to ...
Aspergillus fumigatus is a ubiquitous opportunistic pathogen. This fungus can acquire resistance to ...
Azole antifungal resistance in Aspergillus fumigatus is a worldwide concern. As in most public hospi...
Azole-resistance in Aspergillus fumigatus is emerging and is becoming an increasing problem in the m...
Azole resistance in Aspergillus is emerging in European and Asian countries. As azoles are mainstay ...
Azole resistance in Aspergillus is emerging in European and Asian countries. As azoles are mainstay ...
Azole resistance in Aspergillus has emerged as an escalating problem in health care, and it has been...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Azole resistance in Aspergillus has emerged as an escalating problem in health care, and it has been...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...
Azole resistance is an emerging problem in Aspergillus which impacts the management of aspergillosis...
Background. Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the man...