The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopeptide bonds (crosslinks) between peptide-bound glutamine and lysine residues, but also the transamidation of primary amines to glutamine residues, which ultimately can result into protein polymerisation. Operating with a cysteine/histidine/aspartic acid (Cys/His/Asp) catalytic triad, TGs induce the post-translational modification of proteins at both physiological and pathological conditions (e.g., accumulation of matrices in tissue fibrosis). Because of the disparate biotechnological applications, this large family of protein-remodelling enzymes have stimulated an escalation of interest. In the past 50 years, both mammalian and microbial TGs pol...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Transglutaminases (Tgases) are a widely distributed group of enzymes that catalyse the post-translat...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
In nature, transglutaminases catalyze the formation of amide bonds between proteins to form insolubl...
In nature, transglutaminases catalyze the formation of amide bonds between proteins to form insolubl...
The transglutaminases (TGase; EC2.3.2.13) (R-glutaminyl-peptide-aminase- -glutamyltransferase) are a...
Several proteins from animal and plant origin act as microbial transglutaminase substrate, a crossli...
Several proteins from animal and plant origin act as microbial transglutaminase substrate, a crossli...
Transglutaminases are cross-linking enzymes available for catalyzing covalent isopeptide bond format...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Transglutaminases (Tgases) are a widely distributed group of enzymes that catalyse the post-translat...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent isopepti...
In nature, transglutaminases catalyze the formation of amide bonds between proteins to form insolubl...
In nature, transglutaminases catalyze the formation of amide bonds between proteins to form insolubl...
The transglutaminases (TGase; EC2.3.2.13) (R-glutaminyl-peptide-aminase- -glutamyltransferase) are a...
Several proteins from animal and plant origin act as microbial transglutaminase substrate, a crossli...
Several proteins from animal and plant origin act as microbial transglutaminase substrate, a crossli...
Transglutaminases are cross-linking enzymes available for catalyzing covalent isopeptide bond format...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Various strategies have been explored in the last 20 years to modify the functional properties of pr...
Transglutaminases (Tgases) are a widely distributed group of enzymes that catalyse the post-translat...