Antibody light chains (LCs), formerly considered a waste product of immunoglobulin synthesis, are currently recognized as important players in the activation of the immune response. However, very little is known about the possible immune regulatory functions of LCs. Recently, we reported that hapten-specific LCs coat miRNA-150-carrying exosomes produced by CD8+ suppressor T cells downregulating the contact hypersensitivity (CHS) reaction in an antigen-specific manner, in mice tolerized by intravenous administration of a high dose of hapten-coupled syngeneic erythrocytes. Thus, the current studies aimed at investigating the role of hapten-specific LCs in antigen-specific, exosome-mediated suppression of CHS effector cells. Suppressor T cell-...
International audienceBackground: Mouse bone marrow mast cells (BMMC) have been shown to induce lymp...
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the regulation of maturati...
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the regulation of maturati...
Antibody light chains (LCs), formerly considered a waste product of immunoglobulin synthesis, are cu...
Previously, we showed that mouse delayed-type hypersensitivity (DTH) can be antigen-specifically dow...
Abstract Soon after the discovery of T suppressor cells by Gershon in 1970, it was demonstrated that...
Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten applicat...
Background: T-cell tolerance of allergic cutaneous contact sensitivity (CS) induced in mice by high...
Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten applicat...
<div><p>Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten ...
Nano-vesicles (30-100 nm) with an endosome-derived limiting membrane are called exosomes. These are ...
Exosomes are nanoparticles being released by various types of cells and they often carry functional ...
T-cell mediated immune responses should be regulated to avoid the development of autoimmune or chron...
Exosomes are nano-sized membrane vesicles released from a wide variety of cells, formed in endosomes...
We recently described a novel biotechnological platform for the production of unrestricted cytotoxic...
International audienceBackground: Mouse bone marrow mast cells (BMMC) have been shown to induce lymp...
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the regulation of maturati...
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the regulation of maturati...
Antibody light chains (LCs), formerly considered a waste product of immunoglobulin synthesis, are cu...
Previously, we showed that mouse delayed-type hypersensitivity (DTH) can be antigen-specifically dow...
Abstract Soon after the discovery of T suppressor cells by Gershon in 1970, it was demonstrated that...
Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten applicat...
Background: T-cell tolerance of allergic cutaneous contact sensitivity (CS) induced in mice by high...
Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten applicat...
<div><p>Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten ...
Nano-vesicles (30-100 nm) with an endosome-derived limiting membrane are called exosomes. These are ...
Exosomes are nanoparticles being released by various types of cells and they often carry functional ...
T-cell mediated immune responses should be regulated to avoid the development of autoimmune or chron...
Exosomes are nano-sized membrane vesicles released from a wide variety of cells, formed in endosomes...
We recently described a novel biotechnological platform for the production of unrestricted cytotoxic...
International audienceBackground: Mouse bone marrow mast cells (BMMC) have been shown to induce lymp...
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the regulation of maturati...
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the regulation of maturati...