After birth, the development of hematopoietic cells occurs in the bone marrow. Hematopoietic differentiation is finely tuned by cell-intrinsic mechanisms and lineage-specific transcription factors. However, it is now clear that the bone marrow microenvironment plays an essential role in the maintenance of hematopoietic stem cells (HSC) and their differentiation into more mature lineages. Mesenchymal and endothelial cells contribute to a protective microenvironment called hematopoietic niches that secrete specific factors and establish a direct contact with developing hematopoietic cells. A number of recent studies have addressed in mouse models the specific molecular events that are involved in the cellular crosstalk between hematopoietic s...
Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in both the endo...
Extent: 10p.In the adult mammal, normal haematopoiesis occurs predominantly in the bone marrow, wher...
Because hematopoietic stem cells (HSCs) were found to require a bone marrow (BM) habitat for long-te...
After birth, the development of hematopoietic cells occurs in the bone marrow. Hematopoietic differe...
Abstract Purpose of review: The bone marrow niche is increasingly recognized as heterogeneous with ...
In adult mammals, Hematopoietic stem cells (HSCs) depend on specialized bone marrow (BM) HSC niches ...
The concept of a hematopoietic niche was first proposed in 1978, and the overall concept of a stem c...
Adult hematopoietic stem cells (HSCs) and progenitors (HPCs) reside in the bone marrow, a highly orc...
The hematopoietic stem cell (HSC) is probably the best characterized somatic stem cell and is still ...
Hematopoietic stem cells (HSC) reside in specialized microenvironments known as niches. The niche is...
Hematopoietic stem cell (HSC) niches have been reported at the endosteum or adjacent to bone marrow ...
Abstract: In mammals, hematopoietic stem cells (HSCs), which give rise to all blood cells and their ...
Hematopoietic stem cell (HSC) niches have been reported at the endosteum or adjacent to bone marrow ...
Hematopoietic stem cell (HSC) chemotaxis, adhesion, proliferation, quiescence and differentiation ar...
Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in both the endo...
Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in both the endo...
Extent: 10p.In the adult mammal, normal haematopoiesis occurs predominantly in the bone marrow, wher...
Because hematopoietic stem cells (HSCs) were found to require a bone marrow (BM) habitat for long-te...
After birth, the development of hematopoietic cells occurs in the bone marrow. Hematopoietic differe...
Abstract Purpose of review: The bone marrow niche is increasingly recognized as heterogeneous with ...
In adult mammals, Hematopoietic stem cells (HSCs) depend on specialized bone marrow (BM) HSC niches ...
The concept of a hematopoietic niche was first proposed in 1978, and the overall concept of a stem c...
Adult hematopoietic stem cells (HSCs) and progenitors (HPCs) reside in the bone marrow, a highly orc...
The hematopoietic stem cell (HSC) is probably the best characterized somatic stem cell and is still ...
Hematopoietic stem cells (HSC) reside in specialized microenvironments known as niches. The niche is...
Hematopoietic stem cell (HSC) niches have been reported at the endosteum or adjacent to bone marrow ...
Abstract: In mammals, hematopoietic stem cells (HSCs), which give rise to all blood cells and their ...
Hematopoietic stem cell (HSC) niches have been reported at the endosteum or adjacent to bone marrow ...
Hematopoietic stem cell (HSC) chemotaxis, adhesion, proliferation, quiescence and differentiation ar...
Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in both the endo...
Bone marrow (BM) is a source of hematopoietic stem cells (HSCs). HSCs are localized in both the endo...
Extent: 10p.In the adult mammal, normal haematopoiesis occurs predominantly in the bone marrow, wher...
Because hematopoietic stem cells (HSCs) were found to require a bone marrow (BM) habitat for long-te...