β-Lactamase inhibitors have emerged as an effective alternative to reduce the effects of resistance against β-lactam antibiotics. The Streptomyces genus is known for being an exceptional natural source of antimicrobials and β-lactamase inhibitors such as clavulanic acid, which is largely applied in clinical practice. To protect against the increasing prevalence of multidrug-resistant bacterial strains, new antibiotics and β-lactamase inhibitors need to be discovered and developed. This review will cover an update about the main β-lactamase inhibitors producers belonging to the Streptomyces genus; advanced methods, such as genetic and metabolic engineering, to enhance inhibitor production compared with wild-type stra...
The increasing incidence and prevalence of multidrug resistance (MDR) among contemporary Gram-negati...
Antibiotic resistance caused by β-lactamase production continues to present a growing challenge to t...
The global overuse of antibiotics has led to the emergence of drug-resistant pathogenic bacteria. Ba...
β-Lactamase inhibitors have emerged as an effective alternative to reduce the effects of resist...
\u3b2-Lactamase inhibitors have emerged as an effective alternative to reduce the effects of resista...
The selection of new microorganisms able to produce antimicrobial compounds is hoped for to reduce t...
Emergence of antibiotic resistant pathogens is changing the way scientists look for new antibiotic c...
β-Lactams are the most widely used and effective antibiotics for the treatment of infectious di...
peer reviewedAntibiotic resistance, and the emergence of pan-resistant clinical isolates, seriously ...
  Objective: Clavulanic acid (CA) is a vital agent in the treatment of bacterial infections since ...
The β-lactams have a central place in the antibacterial armamentarium, but the increasing resistance...
Hundred and ten of actinomycete isolates were screened for β-lactamase inhibitors against Staphyloco...
Antibiotic resistance is threatening the medical industry in treating microbial infections. Many org...
The use of the three classical beta-lactamase inhibitors (clavulanic acid, tazobactam, sulbactam) in...
AbstractStreptomyces is a genus of Gram-positive bacteria that grows in various environments, and it...
The increasing incidence and prevalence of multidrug resistance (MDR) among contemporary Gram-negati...
Antibiotic resistance caused by β-lactamase production continues to present a growing challenge to t...
The global overuse of antibiotics has led to the emergence of drug-resistant pathogenic bacteria. Ba...
β-Lactamase inhibitors have emerged as an effective alternative to reduce the effects of resist...
\u3b2-Lactamase inhibitors have emerged as an effective alternative to reduce the effects of resista...
The selection of new microorganisms able to produce antimicrobial compounds is hoped for to reduce t...
Emergence of antibiotic resistant pathogens is changing the way scientists look for new antibiotic c...
β-Lactams are the most widely used and effective antibiotics for the treatment of infectious di...
peer reviewedAntibiotic resistance, and the emergence of pan-resistant clinical isolates, seriously ...
  Objective: Clavulanic acid (CA) is a vital agent in the treatment of bacterial infections since ...
The β-lactams have a central place in the antibacterial armamentarium, but the increasing resistance...
Hundred and ten of actinomycete isolates were screened for β-lactamase inhibitors against Staphyloco...
Antibiotic resistance is threatening the medical industry in treating microbial infections. Many org...
The use of the three classical beta-lactamase inhibitors (clavulanic acid, tazobactam, sulbactam) in...
AbstractStreptomyces is a genus of Gram-positive bacteria that grows in various environments, and it...
The increasing incidence and prevalence of multidrug resistance (MDR) among contemporary Gram-negati...
Antibiotic resistance caused by β-lactamase production continues to present a growing challenge to t...
The global overuse of antibiotics has led to the emergence of drug-resistant pathogenic bacteria. Ba...