Novel drugs targeting TNF-alpha are available for treatment of RA. Fibroblast-like synoviocytes (FLSs) play a fundamental role in RA progression, through their expansion caused in part by resistance to cell death induction. The aim of our study was to determine the effects of different anti-TNF-alpha agents on FLS apoptosis
To investigate the anti-apoptotic role of tumor necrosis factor-a (TNF-a) and its signaling pathways...
Objective: Injection of agonistic anti-Fas antibody was shown to decrease disease symptoms in arthri...
<p>RA FLS were stimulated with IL-17A (50 or 100 ng/ml) and/or TNF (1 or 10 ng/ml) for 24 h and syno...
Novel drugs targeting TNF-alpha are available for treatment of RA. Fibroblast-like synoviocytes (FLS...
International audienceRheumatoid Arthritis (RA) is a chronic inflammatory disease affecting synovial...
Fibroblast-like synoviocytes (FLS) are mesenchymal-derived cells that play an important role in the ...
Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by progressive bon...
The introduction of TNF- alpha -inhibiting biologicals has been a major therapeutic breakthrough in ...
We have recently demonstrated Fas-mediated apoptosis in the synovium of patients with rheumatoid art...
A hallmark of rheumatoid arthritis ( RA) is the pseudotumoral expansion of fibroblast- like synovioc...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
To investigate the anti-apoptotic role of tumor necrosis factor-a (TNF-a) and its signaling pathways...
Objective: Injection of agonistic anti-Fas antibody was shown to decrease disease symptoms in arthri...
<p>RA FLS were stimulated with IL-17A (50 or 100 ng/ml) and/or TNF (1 or 10 ng/ml) for 24 h and syno...
Novel drugs targeting TNF-alpha are available for treatment of RA. Fibroblast-like synoviocytes (FLS...
International audienceRheumatoid Arthritis (RA) is a chronic inflammatory disease affecting synovial...
Fibroblast-like synoviocytes (FLS) are mesenchymal-derived cells that play an important role in the ...
Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by progressive bon...
The introduction of TNF- alpha -inhibiting biologicals has been a major therapeutic breakthrough in ...
We have recently demonstrated Fas-mediated apoptosis in the synovium of patients with rheumatoid art...
A hallmark of rheumatoid arthritis ( RA) is the pseudotumoral expansion of fibroblast- like synovioc...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
Rheumatoid arthritis (RA) is an autoimmune disease caused by inflammation of the synovium and charac...
To investigate the anti-apoptotic role of tumor necrosis factor-a (TNF-a) and its signaling pathways...
Objective: Injection of agonistic anti-Fas antibody was shown to decrease disease symptoms in arthri...
<p>RA FLS were stimulated with IL-17A (50 or 100 ng/ml) and/or TNF (1 or 10 ng/ml) for 24 h and syno...