Cell senescence is associated with the secretion of many factors, the so-called “senescence-associated secretory phenotype”, which may alter tissue microenvironment, stimulating the organism to clean up senescent cells and replace them with newly divided ones. Therefore, although no longer dividing, these cells are still metabolically active and influence the surrounding tissue. Much attention has been recently focused not only on soluble factors released by senescent cells, but also on extracellular vesicles as conveyors of senescence signals outside the cell. Here, we give an overview of the role of extracellular vesicles in biological processes and signaling pathways related to senescence and aging
Abstract Rejuvenation of an old organism was achieved in heterochronic parabiosis experiments, impli...
Cellular senescence, a process that imposes permanent proliferative arrest on cells in response to v...
Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough unders...
Cell senescence is associated with the secretion of many factors, the so-called “senescence-associat...
Extracellular vesicles (EVs) are membrane-enclosed particles secreted by cells and circulating in bo...
Abstract Cellular senescence is a persistently hypoproliferative state with diverse stressors in a s...
In recent decades, extracellular vesicles have been recognized as “very important particles” (VIPs) ...
Aging is associated with an alteration of intercellular communication. These changes in the extracel...
Communication between cells is quintessential for biological function and cellular homeostasis. Memb...
Communication between cells is quintessential for biological function and cellular homeostasis. Memb...
Abstract Extracellular vesicles (EVs) are released by many different cell types throughout the body ...
A more comprehensive understanding of the human ageing process is required to help mitigate the incr...
To summarize the scientific evidence regarding the effects of environmental exposures on extracellul...
Cellular senescence is viewed as an irreversible cell-cycle arrest mechanism involving a complexity ...
Parabiosis experiments in mice demonstrated that a young environment could partially rejuvenate mult...
Abstract Rejuvenation of an old organism was achieved in heterochronic parabiosis experiments, impli...
Cellular senescence, a process that imposes permanent proliferative arrest on cells in response to v...
Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough unders...
Cell senescence is associated with the secretion of many factors, the so-called “senescence-associat...
Extracellular vesicles (EVs) are membrane-enclosed particles secreted by cells and circulating in bo...
Abstract Cellular senescence is a persistently hypoproliferative state with diverse stressors in a s...
In recent decades, extracellular vesicles have been recognized as “very important particles” (VIPs) ...
Aging is associated with an alteration of intercellular communication. These changes in the extracel...
Communication between cells is quintessential for biological function and cellular homeostasis. Memb...
Communication between cells is quintessential for biological function and cellular homeostasis. Memb...
Abstract Extracellular vesicles (EVs) are released by many different cell types throughout the body ...
A more comprehensive understanding of the human ageing process is required to help mitigate the incr...
To summarize the scientific evidence regarding the effects of environmental exposures on extracellul...
Cellular senescence is viewed as an irreversible cell-cycle arrest mechanism involving a complexity ...
Parabiosis experiments in mice demonstrated that a young environment could partially rejuvenate mult...
Abstract Rejuvenation of an old organism was achieved in heterochronic parabiosis experiments, impli...
Cellular senescence, a process that imposes permanent proliferative arrest on cells in response to v...
Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough unders...