Coal workers’ pneumoconiosis (CWP) has been associated with abnormalities in the extracellular matrix remodeling, as well as aberrant matrix metalloproteinases (MMPs) in lung tissues. We investigated the association of three functional polymorphisms in MMP gene promoters (MMP1 rs1799750, MMP2 rs2285053 and MMP3 rs522616) with the risk of CWP. A total of 693 CWP cases and 690 controls were included in a case-control study. Genotype analysis was performed by the TaqMan method. Statistically significant differences were found in distributions of MMP3 rs522616 under a recessive model (p = 0.047) between CWP cases and controls. In the stratification analysis, individuals with MMP3 rs522616 GG genotype decreased the risk of CWP (adjusted OR = 0.7...
BACKGROUND: Genetic factors play a role in chronic obstructive pulmonary disease (COPD) but are poor...
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological functions....
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological functions....
and coal workers' pneumoconiosis (CWP) risk in a Chinese population.) were genotyped and analyzed i...
Coal workers' pneumoconiosis (CWP), resulting from the inhalation of silica-containing coal mine dus...
Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation and fibrotic n...
Background: Coal workers ’ pneumoconiosis (CWP), resulting from the inhalation of silica-containing ...
Background: Matrix metalloproteinases (MMPs) are capable of degrading and modifying most components ...
D ow nloaded from 2 The MMPs (Matrix Metalloproteinases) are a family of secreted zinc metalloprotea...
ow nloaded from 2ABSTRACT Matrix metalloproteinases (MMPs) are proteolytic enzymes that regulate var...
and coal workers' pneumoconiosis (CWP) risk in a Chinese population. were genotyped and analyzed in...
Abstract Background Matrix metalloproteases (MMPs) are proteolytic enzymes that contribute to all st...
BACKGROUND: Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation an...
Extracellular matrix formation (ECM) and remodeling are critical events related to the pathogenesis ...
Matrix metalloproteinases; (MMPs) play an important role in several steps of cancer development. A s...
BACKGROUND: Genetic factors play a role in chronic obstructive pulmonary disease (COPD) but are poor...
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological functions....
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological functions....
and coal workers' pneumoconiosis (CWP) risk in a Chinese population.) were genotyped and analyzed i...
Coal workers' pneumoconiosis (CWP), resulting from the inhalation of silica-containing coal mine dus...
Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation and fibrotic n...
Background: Coal workers ’ pneumoconiosis (CWP), resulting from the inhalation of silica-containing ...
Background: Matrix metalloproteinases (MMPs) are capable of degrading and modifying most components ...
D ow nloaded from 2 The MMPs (Matrix Metalloproteinases) are a family of secreted zinc metalloprotea...
ow nloaded from 2ABSTRACT Matrix metalloproteinases (MMPs) are proteolytic enzymes that regulate var...
and coal workers' pneumoconiosis (CWP) risk in a Chinese population. were genotyped and analyzed in...
Abstract Background Matrix metalloproteases (MMPs) are proteolytic enzymes that contribute to all st...
BACKGROUND: Coal workers' pneumoconiosis (CWP) is characterized by chronic pulmonary inflammation an...
Extracellular matrix formation (ECM) and remodeling are critical events related to the pathogenesis ...
Matrix metalloproteinases; (MMPs) play an important role in several steps of cancer development. A s...
BACKGROUND: Genetic factors play a role in chronic obstructive pulmonary disease (COPD) but are poor...
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological functions....
The H19 is a kind of long noncoding RNA, which has been implicated in multiple biological functions....