Appropriate innate and adaptive immune responses are essential for protection and resolution against chemical, physical or biological insults. Immune cell polarization is fundamental in orchestrating distinct phases of inflammation, specifically acute phase responses followed by resolution and tissue repair. Dysregulation of immune cell and inflammatory responses is a hallmark of multiple diseases encompassing atherosclerosis, rheumatoid arthritis, psoriasis and metabolic syndromes. A master transcriptional mediator of diverse inflammatory signaling and immune cell function is NF-κB, and altered control of this key regulator can lead to an effective switch from acute to chronic inflammatory responses. Members of the nuclear receptor (NR) su...
Microglia cells fulfill key homeostatic functions and essentially contribute to host defense within ...
Nr4a1-3 encode a small family of orphan nuclear hormone receptors with transcriptional activity. The...
AbstractThe NR4A subfamily of nuclear receptors consists of three mammalian members: Nur77, Nurr1, a...
To understand chronic inflammatory diseases such as atherosclerosis, we require in-depth knowledge o...
The NR4A1–NR4A3 (Nur77, Nurr1, and Nor-1) subfamily of nuclear receptors is a group of immediate ear...
The nuclear receptor sub-family 4 group A (NR4A) family are early response genes that encode protein...
Adenosine receptor–mediated regulation of monocyte/macrophage inflammatory responses is critical in ...
Uptake of apoptotic cells (ACs) by macrophages ensures the nonimmunogenic clearance of dying cells, ...
The inflammatory response is of major importance in host defence, but is involved in all acute and c...
Rationale: NR4A1 (Nur77) is a nuclear receptor that is expressed in macrophages and within atheroscl...
The Nuclear receptor subfamily 4 group A (Nr4as) are members of the superfamily of nuclear receptors...
Rationale: NR4A1 (Nur77) is a nuclear receptor that is expressed in macrophages and within atheroscl...
The NR4A subfamily of nuclear receptors consists of three mammalian members: Nur77, Nurr1, and NOR-1...
The mechanisms committed in the activation and response of vascular and inflammatory immune cells pl...
Objective—Atherosclerosis is an inflammatory disease in which macrophage activation and lipid loadin...
Microglia cells fulfill key homeostatic functions and essentially contribute to host defense within ...
Nr4a1-3 encode a small family of orphan nuclear hormone receptors with transcriptional activity. The...
AbstractThe NR4A subfamily of nuclear receptors consists of three mammalian members: Nur77, Nurr1, a...
To understand chronic inflammatory diseases such as atherosclerosis, we require in-depth knowledge o...
The NR4A1–NR4A3 (Nur77, Nurr1, and Nor-1) subfamily of nuclear receptors is a group of immediate ear...
The nuclear receptor sub-family 4 group A (NR4A) family are early response genes that encode protein...
Adenosine receptor–mediated regulation of monocyte/macrophage inflammatory responses is critical in ...
Uptake of apoptotic cells (ACs) by macrophages ensures the nonimmunogenic clearance of dying cells, ...
The inflammatory response is of major importance in host defence, but is involved in all acute and c...
Rationale: NR4A1 (Nur77) is a nuclear receptor that is expressed in macrophages and within atheroscl...
The Nuclear receptor subfamily 4 group A (Nr4as) are members of the superfamily of nuclear receptors...
Rationale: NR4A1 (Nur77) is a nuclear receptor that is expressed in macrophages and within atheroscl...
The NR4A subfamily of nuclear receptors consists of three mammalian members: Nur77, Nurr1, and NOR-1...
The mechanisms committed in the activation and response of vascular and inflammatory immune cells pl...
Objective—Atherosclerosis is an inflammatory disease in which macrophage activation and lipid loadin...
Microglia cells fulfill key homeostatic functions and essentially contribute to host defense within ...
Nr4a1-3 encode a small family of orphan nuclear hormone receptors with transcriptional activity. The...
AbstractThe NR4A subfamily of nuclear receptors consists of three mammalian members: Nur77, Nurr1, a...