Add to ORKGA label-free quantitative proteomic approach has been undertaken to study the effects of the peptide on the proteins involved in the modulated metabolic pathways, in particular those involved in the folate metabolism. Structure-activity relationships (SAR) have been performed to improve the lead peptide pharmacodynamics. All the compounds have been assayed and a protein profile set was studied to mark and validate their behavior as inhibitor of OC cell growth
Though many proteins have been identified as relevant to cancer pathogenicity, very few are now targ...
Proteomics and bioinformatics are a useful combined technology for the characterization of protein e...
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in femal...
A label-free quantitative proteomic approach has been undertaken to study the effects of the peptide...
The preclinical study of the mechanism of action of anticancer small molecules is challenging due to...
The preclinical study of the mechanism of action of anticancer small molecules is challenging due to...
Many efforts to improve survival of patients affected by Ovarian Cancer (OC) have focused on more e...
The preclinical study of the mechanism of action of anticancer small molecules is challenging due to...
Many efforts to improve survival of patients affected by Ovarian Cancer (OC) have focused on more ef...
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting ...
New selective, efficacious chemotherapy agents are in demand as traditional drugs display side effec...
Proteomics and bioinformatics are a useful combined technology for the characterization of protein e...
CIGB-552 is a cell-penetrating peptide that exerts in vitro and in vivo antitumor effect on cancer c...
Despite significant progress in the development of anti-cancer drugs, there is still a need for nove...
International audienceThis review is an attempt to illustrate the diversity of peptides reported for...
Though many proteins have been identified as relevant to cancer pathogenicity, very few are now targ...
Proteomics and bioinformatics are a useful combined technology for the characterization of protein e...
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in femal...
A label-free quantitative proteomic approach has been undertaken to study the effects of the peptide...
The preclinical study of the mechanism of action of anticancer small molecules is challenging due to...
The preclinical study of the mechanism of action of anticancer small molecules is challenging due to...
Many efforts to improve survival of patients affected by Ovarian Cancer (OC) have focused on more e...
The preclinical study of the mechanism of action of anticancer small molecules is challenging due to...
Many efforts to improve survival of patients affected by Ovarian Cancer (OC) have focused on more ef...
Proteomic approach to the identification of early phase biomarker for anticancer peptides targeting ...
New selective, efficacious chemotherapy agents are in demand as traditional drugs display side effec...
Proteomics and bioinformatics are a useful combined technology for the characterization of protein e...
CIGB-552 is a cell-penetrating peptide that exerts in vitro and in vivo antitumor effect on cancer c...
Despite significant progress in the development of anti-cancer drugs, there is still a need for nove...
International audienceThis review is an attempt to illustrate the diversity of peptides reported for...
Though many proteins have been identified as relevant to cancer pathogenicity, very few are now targ...
Proteomics and bioinformatics are a useful combined technology for the characterization of protein e...
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in femal...