Add to ORKGPriamry hyeprcholesterolemai associates with increased rates of cholesterol 27 hydroxylation which normalizes with statin treatment. the correlation between plasma cholesterol levels and 27 hydroxylation support the view that the latter may act as a compensatory mechanism in a condition of larger plasma cholesterol pool. A regulatory roel for uclear receptors seems reasonable.These dta may encourage novel pharmacplogical approaches for the managment of hypercholesterolemia and prevention of atherosclerosi
Several processes are involved in control of plasma cholesterol levels, e.g., intestinal cholesterol...
Regulation of bile acid synthesis, a key determinant of cholesterol homeostasis, is still incomplete...
The aim of the theses is to characterize the mechanism that participate in the regulation of activit...
Priamry hyeprcholesterolemai associates with increased rates of cholesterol 27 hydroxylation which n...
BACKGROUND AND AIMS: The first step in the alternative pathway of bile acid biosynthesis is the 27-h...
BACKGROUND. The first step in the alternate biosynthetic pathway of bile acid synthesis from cholest...
Over the last few years important progress has been made on the quantitation of cholesterol 7 alpha-...
An increased level of plasma cholesterol is associated with premature development of atherosclerosis...
The rates of cholesterol 7-alpha-hydroxylation (the first and rate-limiting step of bile acid synthe...
Excess plasma cholesterol, in particular high levels of LDL cholesterol, is a major risk factor for ...
Background: Cholesterol elimination occurs through bile acid synthesis that starts within the liver ...
Cholesterol is essential for normal growth and development in mammals. However, excess cholesterol c...
In conditions of chronically stimulated bile acid syntehsis , obtained by pharmacological interrupti...
The effects of newly synthesized cholesterol availability on bile acid synthesis are largely unknown...
Cholesterol 7α-hydroxylase (CYP7A1) is an enzyme catalyzing the first step of conversion of choleste...
Several processes are involved in control of plasma cholesterol levels, e.g., intestinal cholesterol...
Regulation of bile acid synthesis, a key determinant of cholesterol homeostasis, is still incomplete...
The aim of the theses is to characterize the mechanism that participate in the regulation of activit...
Priamry hyeprcholesterolemai associates with increased rates of cholesterol 27 hydroxylation which n...
BACKGROUND AND AIMS: The first step in the alternative pathway of bile acid biosynthesis is the 27-h...
BACKGROUND. The first step in the alternate biosynthetic pathway of bile acid synthesis from cholest...
Over the last few years important progress has been made on the quantitation of cholesterol 7 alpha-...
An increased level of plasma cholesterol is associated with premature development of atherosclerosis...
The rates of cholesterol 7-alpha-hydroxylation (the first and rate-limiting step of bile acid synthe...
Excess plasma cholesterol, in particular high levels of LDL cholesterol, is a major risk factor for ...
Background: Cholesterol elimination occurs through bile acid synthesis that starts within the liver ...
Cholesterol is essential for normal growth and development in mammals. However, excess cholesterol c...
In conditions of chronically stimulated bile acid syntehsis , obtained by pharmacological interrupti...
The effects of newly synthesized cholesterol availability on bile acid synthesis are largely unknown...
Cholesterol 7α-hydroxylase (CYP7A1) is an enzyme catalyzing the first step of conversion of choleste...
Several processes are involved in control of plasma cholesterol levels, e.g., intestinal cholesterol...
Regulation of bile acid synthesis, a key determinant of cholesterol homeostasis, is still incomplete...
The aim of the theses is to characterize the mechanism that participate in the regulation of activit...