Applications of ring-closing alkene metathesis (RCM) in acyclic α- and β-peptides and closely related systems are reviewed, with a special emphasis on the structural and pharmacological effects of cyclization by RCM
Abstract: A comprehensive study on the synthesis and ring-closing metathesis (RCM) of a,b-dehydro-am...
ABSTRACT: Olefin metathesis has emerged as a promising strategy for modulating the stability and act...
Macrocyclization can be used to constrain peptides in their bioactive conformations, thereby support...
Ring-closing metathesis (RCM) with α,α-diallylglycyl peptides is shown to furnish α,α-cyclopentenylg...
The synthesis of a series of “amide to amide” cyclized peptides by ring-closing metathesis (RCM) as ...
This review surveys developments in the field of ring-closing metathesis and cross-metathesis reacti...
Copyright © 2006 Elsevier B.V. All rights reserved.Three new classes of conformationally constrained...
Bicyclic peptides are promising scaffolds for the development of inhibitors of biological targets th...
Understanding protein structure and function is central for the development of therapeutics for the ...
Here we highlight our recent results of the application of ring-closing metathesis and ring-closing ...
The ring-closing metathesis reaction can be used to cross-link allylated serine residues situated at...
Peptidomimetics have found wide application as biostable, bioavailable, and often potent mimics of n...
This thesis investigates the application of cross metathesis and ring-closing metathesis to amino ac...
Contains fulltext : 58942.pdf (publisher's version ) (Closed access)The applicatio...
In this letter, we describe the ring-rearrangement metathesis (RRM) of bicyclic amino acid derivativ...
Abstract: A comprehensive study on the synthesis and ring-closing metathesis (RCM) of a,b-dehydro-am...
ABSTRACT: Olefin metathesis has emerged as a promising strategy for modulating the stability and act...
Macrocyclization can be used to constrain peptides in their bioactive conformations, thereby support...
Ring-closing metathesis (RCM) with α,α-diallylglycyl peptides is shown to furnish α,α-cyclopentenylg...
The synthesis of a series of “amide to amide” cyclized peptides by ring-closing metathesis (RCM) as ...
This review surveys developments in the field of ring-closing metathesis and cross-metathesis reacti...
Copyright © 2006 Elsevier B.V. All rights reserved.Three new classes of conformationally constrained...
Bicyclic peptides are promising scaffolds for the development of inhibitors of biological targets th...
Understanding protein structure and function is central for the development of therapeutics for the ...
Here we highlight our recent results of the application of ring-closing metathesis and ring-closing ...
The ring-closing metathesis reaction can be used to cross-link allylated serine residues situated at...
Peptidomimetics have found wide application as biostable, bioavailable, and often potent mimics of n...
This thesis investigates the application of cross metathesis and ring-closing metathesis to amino ac...
Contains fulltext : 58942.pdf (publisher's version ) (Closed access)The applicatio...
In this letter, we describe the ring-rearrangement metathesis (RRM) of bicyclic amino acid derivativ...
Abstract: A comprehensive study on the synthesis and ring-closing metathesis (RCM) of a,b-dehydro-am...
ABSTRACT: Olefin metathesis has emerged as a promising strategy for modulating the stability and act...
Macrocyclization can be used to constrain peptides in their bioactive conformations, thereby support...
DOI
Add to ORKG