Vitamin D deficiency is associated with type 2 diabetes mellitus in HIV infection.

Szep Z
Shah SS
Lo Re V. 3rd
Ratcliffe SJ
Tebas P.
GUARALDI, Giovanni
ORLANDO, Gabriella
CARLI, FEDERICA
ROSSI, Rosario
ROCHIRA, Vincenzo

Open link

Publication date

January 2011

DOI

10.1097/QAD.0b013e328342fdfd

Publisher

Ovid Technologies (Wolters Kluwer Health)

ISSN

0269-9370

Abstract

BACKGROUND: Metabolic complications, including type 2 diabetes mellitus and metabolic syndrome, are increasingly recognized among HIV-infected individuals. Low vitamin D levels increase the risk of type 2 diabetes mellitus, and vitamin D supplementation has been shown to decrease the risk of type 2 diabetes mellitus in patients without HIV infection.OBJECTIVES: The primary objective was to determine whether vitamin D deficiency (serum 25-hyrdoxyvitamin D <20 ng/ml) was associated with type 2 diabetes mellitus among HIV-infected patients. Our secondary objective was to determine whether vitamin D deficiency was associated with metabolic syndrome in HIV.METHODS: We conducted a cross-sectional study among participants enrolled in the prospecti...