The preparation of monoarylidene and both symmetrical and unsymmetrical bisarylidene derivatives of piperazine-2,5-dione is described. The use of 1,4-diacetylpiperazine-2,5-dione make it possible to prepare unsymmetrical bisarylidenes. The introduction of a dicyanomethylene moiety into the para position of one of the arylidene groups gave a remarkable deepening in the colour of the resulting compounds 11 and 16
The first general procedure is described for the synthesis of novel bisarylmethylidenes of 2-methoxy...
New classes of monomers containing heterocyclic groups have been prepared in good yield from readily...
Piperazine scaffolds are amongst the most extensively used backbones in medicinal chemistry and many...
The activity of pharmacologically active compounds can be increased by presenting a drug in a define...
1,4-disubstituted piperazine-2,5-diones were prepared by intermolacular cyclization of two molecules...
Condensation of 1,4-diacetylpiperazine-2,5-dione with 2-chloroquinoline-3-carbaldehyde has been appl...
Condensation of l,4-diacetylpiperazine-2,5-dione with 2-chloroquinoline-3-carbaldehyde has been appl...
Piperazines are widely used as central elements in the construction of bioactive molecules. Herein, ...
A few 1, 4-bis-polynitrophenylpiperazines have been obtained by the condensation of reactive halogen...
International audienceIn this paper, we describe the synthesis of a wide range of new rod-like conju...
It is known that polyhalogeno-nitro-1,3-butadienes are important starting materials for the synthesi...
[[abstract]]A new generation of a flexible bipyridine-based ligand, 1,4-bis(4-pyridyl)piperazine, wi...
Novel bis(2-oxo-2H-chromene) as well as bis(2-imino-2H-chromene) derivatives incorporating piperazin...
New tetrahydroisoquinoline-5,7-dicarbonitrile derivatives have been synthesized by piperazine hydrat...
In this work the aldol condensation reactions of 2,5-piperazinediones with carbonyl compounds were i...
The first general procedure is described for the synthesis of novel bisarylmethylidenes of 2-methoxy...
New classes of monomers containing heterocyclic groups have been prepared in good yield from readily...
Piperazine scaffolds are amongst the most extensively used backbones in medicinal chemistry and many...
The activity of pharmacologically active compounds can be increased by presenting a drug in a define...
1,4-disubstituted piperazine-2,5-diones were prepared by intermolacular cyclization of two molecules...
Condensation of 1,4-diacetylpiperazine-2,5-dione with 2-chloroquinoline-3-carbaldehyde has been appl...
Condensation of l,4-diacetylpiperazine-2,5-dione with 2-chloroquinoline-3-carbaldehyde has been appl...
Piperazines are widely used as central elements in the construction of bioactive molecules. Herein, ...
A few 1, 4-bis-polynitrophenylpiperazines have been obtained by the condensation of reactive halogen...
International audienceIn this paper, we describe the synthesis of a wide range of new rod-like conju...
It is known that polyhalogeno-nitro-1,3-butadienes are important starting materials for the synthesi...
[[abstract]]A new generation of a flexible bipyridine-based ligand, 1,4-bis(4-pyridyl)piperazine, wi...
Novel bis(2-oxo-2H-chromene) as well as bis(2-imino-2H-chromene) derivatives incorporating piperazin...
New tetrahydroisoquinoline-5,7-dicarbonitrile derivatives have been synthesized by piperazine hydrat...
In this work the aldol condensation reactions of 2,5-piperazinediones with carbonyl compounds were i...
The first general procedure is described for the synthesis of novel bisarylmethylidenes of 2-methoxy...
New classes of monomers containing heterocyclic groups have been prepared in good yield from readily...
Piperazine scaffolds are amongst the most extensively used backbones in medicinal chemistry and many...