Tetrasubstituted pyrrolidines representing analogs of homoproline weresynthesized by three-component condensation of aryl(heteroaryl)aldehydes, asparagineand N-methylmaleimide (NMM). Compounds with (1S*, 3R*, 3aS*, 6aR*)-configurationat the corresponding carbon positions of the bicyclic pyrrolidine ring could be isolated ona preparative scale
An efficient route to 3-benzylpyrrolidines using a zirconium-mediated cyclisation both in solution a...
An unexpected outcome of a reaction unveiled a new method to obtain N-Cbz-L-prolinol from N-Cbz-L-gl...
An efficient diversity-oriented strategy has been developed for the solution-phase parallel synthesi...
Highly functionalized 5-membered N-heterocyclic compounds, 4-aryl-3-chloro-5-methoxy-1-methyl-3-pyrr...
The purpose of this investigation was the synthesis and study of the configuration of various 4-meth...
The reaction of 2,3-butanedione, ethyl pyruvate and phenylglyoxal with \u3b2-nitrostyrene and L-prol...
The enantioselective synthesis of substituted pyrrolidines through a mild Lewis-acid catalyzed three...
International audienceNew methods for the preparation of 2-azabicyclo[3.1.0]hexane compounds (2,3- m...
International audienceThe diastereoselective addition of allyl zinc and allylindium derivatives to α...
A practical and scalable synthesis of a Fmoc-protected tricyclic dipeptide mimetic (6), that is, a 1...
Efficient routes for the gram-scale preparation of the proline analogues that bear a phenyl substitu...
Six new 3-pyrrolin-2-one derivatives were synthesized via the condensation reaction of amino acid es...
The development of an asymmetric ‘clip-cycle’ synthesis of 2,2- and 3,3-disubstituted pyrrolidines a...
The synthesis of unnatural pyrrolizidines has been studied using a multicomponent-domino process inv...
Addition of vinylmagnesium bromide across chiral achloroN-tert-butanesulfinyl ketimines afforded 3-a...
An efficient route to 3-benzylpyrrolidines using a zirconium-mediated cyclisation both in solution a...
An unexpected outcome of a reaction unveiled a new method to obtain N-Cbz-L-prolinol from N-Cbz-L-gl...
An efficient diversity-oriented strategy has been developed for the solution-phase parallel synthesi...
Highly functionalized 5-membered N-heterocyclic compounds, 4-aryl-3-chloro-5-methoxy-1-methyl-3-pyrr...
The purpose of this investigation was the synthesis and study of the configuration of various 4-meth...
The reaction of 2,3-butanedione, ethyl pyruvate and phenylglyoxal with \u3b2-nitrostyrene and L-prol...
The enantioselective synthesis of substituted pyrrolidines through a mild Lewis-acid catalyzed three...
International audienceNew methods for the preparation of 2-azabicyclo[3.1.0]hexane compounds (2,3- m...
International audienceThe diastereoselective addition of allyl zinc and allylindium derivatives to α...
A practical and scalable synthesis of a Fmoc-protected tricyclic dipeptide mimetic (6), that is, a 1...
Efficient routes for the gram-scale preparation of the proline analogues that bear a phenyl substitu...
Six new 3-pyrrolin-2-one derivatives were synthesized via the condensation reaction of amino acid es...
The development of an asymmetric ‘clip-cycle’ synthesis of 2,2- and 3,3-disubstituted pyrrolidines a...
The synthesis of unnatural pyrrolizidines has been studied using a multicomponent-domino process inv...
Addition of vinylmagnesium bromide across chiral achloroN-tert-butanesulfinyl ketimines afforded 3-a...
An efficient route to 3-benzylpyrrolidines using a zirconium-mediated cyclisation both in solution a...
An unexpected outcome of a reaction unveiled a new method to obtain N-Cbz-L-prolinol from N-Cbz-L-gl...
An efficient diversity-oriented strategy has been developed for the solution-phase parallel synthesi...