In Silico Structural, Functional and Phylogenetic Analyses of Corynebacterium Aspartokinase: An Enzyme of Aspartate Family of Amino Acids

Aspartokinase is the enzyme of the aspartate family of amino acid biosynthesis that catalyzes first reaction in biosynthesis of Aspartate family. This enzyme has an important role for hyper production of the Lysine or methionine or threonine by microbial fermentation. The present study was undertaken to determine the in silico analysis of the aspartokinase of Corynebacteriumglutamicum. In silicoanalysis ofAspartokinase protein of Corynebacteriumglutamicumrevealed that it is a thermostable, acidic protein having molecular weight of about 45kDa. The 3D structure and protein model with functional characters of this protein has predicted. This computational analysis might assist with useful information required during wet lab experiments