To study analyze maternal serum alpha-fetoprotein as a biomarker of placental adherence in low lying placenta

Background: To study the place of Maternal Serum Alfa Feto Protein (MSAFP) as a biomarker of placental adherence in low lying placenta, and to study maternal outcome in the study group.Methods: This is a prospective observational study analyzing the conditions and the data of 90 cases with low lying placenta in a tertiary care hospital. The analysis was done for the association of MSAFP with MRI, perinatal and maternal outcome.Results: The level of MSAFP was found higher in 14 out of 15 cases (93.3%) of placenta previa with placental adherence. There was significant surgical intervention (80%) and increased maternal morbidity (68.8%) in the study group with placental adherence and raised MSAFP respectively.Conclusions: MSAFP is an important biomarker for prognostication of placental adherence in low lying placenta