Evaluation of the validity of risk malignancy index in clinically diagnosed ovarian masses and to compare it with the validity of individual constituent parameter of risk malignancy index

Background: Pre-operative knowledge regarding the nature of ovarian mass is necessary in order to plan surgery. Risk malignancy index (RMI) is a simple scoring system based on three factors serum CA 125, USG score & menopausal status. The RMI was interpreted as 1) score > 250 = high risk, 2) 25-250 =intermediate risk, 3) score <25 = low risk. The objective of the study was, 1) to evaluate risk malignancy index (RMI) in pre-operatively clinically diagnosed ovarian mass, 2) to compare the validity of individual parameter in RMI i.e. menopausal status, serum CA 125 & USG score with validity of RMI as a comprehensive index .Methods: This was an observational study conducted at department of obstetrics and gynaecology, GMCH Aurangabad from October 2012 to 2014 with sample size of 102 cases with clinical diagnosis of ovarian mass admitted for laparotomy. The validity of RMI and validity of individual parameter was calculated and compared.Results: RMI showed better sensitivity of 85.71%, specificity of 85.07% and ppv of 75%, npv of 91.93% and accuracy of 82.29% as compared to validity of individual parameters.Conclusions: RMI is simple, valuable & highly reliable in pre-operative differentiation of malignant & benign lesion. Simplicity and applicability of this method in the primary evaluation of patients with pelvic masses makes it a good option in daily clinical gynaecological practice.