Association of fructosamine, glycated albumin and hba1c in prediabetes, diabetic and associated complications

Background: The efficient diagnosis and accurate monitoring of diabetic patients are cornerstones for reducing the risk of diabetic complications. Aims: Aim of the study is to assess level of Glycated hemoglobin, serum fructosamine, Glycated albumin in Prediabetes, type-2 Diabetic patients with and with out microvascular complications and to find out their correlation with diabetes complications. Materials and methods: This is a Case-control study in200 subjects will be involved in this study and they will be divided into 4 groups. The controls and subjects (cases) were age and gender matched. Samples collected from patients after obtaining Informed written Consent. Results: .  Differences between these groups for serum fructosamine, glycated albumin were statistically significant. Glycated albumin showed excellent correlation with fructosamine across groups (p ≤ 0.0003 in all groups) and correlation coefficient r was >0.9 in groups 2 and 3. Serum fructosamine and glycated albumin correlated well with FBS, PP2BS, HbA1C in groups 2, 3 and 4. Irrespective of the groups, serum glycated albumin showed excellent correlation with serum fructosamine.