Antidiabetic property of ethanol extract of pelargonium graveolens with constituents chemical screening

Objects: The phytochemical screening and the antihyperglycemic impact of Pelargonium gravelens were performed to judge the impact of ethanol extract using alloxan-induced diabetic rats. Methods: Intragastric ethanolic extract amount level of 220 mg/kg body weight were given to alloxan-encouraged diabetic male albino rats for four weeks. Diabetic control rats assumed the equivalent quantity of the vehicle (Dimethylsulfoxide, DMSO) were processed together with the former group. The serum insulin, liver glycogen assay and oral glucose tolerance tests were done. The chemical screening of P. graveolens specified the existence of carbohydrates, glycosides, triterpenes, cardenolides, saponins, sterols, tannins, flavonoids and catechins. Results: The diabetic-treated rats with the ethanolic extract of P. graveolens performed clear improvement of the declined glucose tolerance and hepatic glycogen content without associated excess in serum insulin concentration. Conclusions: ethanol extract of P. Graveolens improved the glucose tolerance of alloxan-treated diabetic rats