Comparative evaluation of effect of diode laser as an adjunct to scaling and root planing and scaling and root planing alone on clinical parameters and gingival crevicular fluid interlukin-10 level in chronic periodontitis

The aim of the study was to compare and evaluate the effect of diode laser as an adjunct to scaling and root planing and scaling and root planing alone on clinical parameters and Gingival Crevicular Fluid (GCF) interlukin-10 level in chronic periodontitis. Ten chronic periodontitis patients were selected. As it was a split mouth study, two sites with deepest pocket one in each quadrant were randomly assigned for scaling and root planing (SRP) and SRP+ diode laser treatment. Plaque index, gingival index, probing depth, and clinical attachment level were measured at baseline and at 3months after treatment. The GCF levels of interleukin-10 (IL-10) were analyzed by enzyme-linked immunosorbent assay. Test group showed significantly better outcome compared to the control group in all clinical parameters (PI, GI, PD and CAL). The total amount of IL-10 increased after treatment in both test and control groups. From baseline to three months, the SRP with Diode laser group demonstrated a substantial rise in IL-10 levels, demonstrating how lasers can improve nonsurgical periodontal treatment results. Thus, diode laser when used in adjunct to SRP, the levels of IL-10 which is an anti-inflammatory cytokine, significantly increased which indicated reduced inflammation of the tissues