Chapter 12: The Moon Shots Program and a Model of Translational Research

Dr. Bast begins with general observations about how translational research has evolved at MD Anderson under Dr. Ronald DePinho\u27s leadership as president. He notes that Dr. DePinho\u27s Moon Shots Program is the most direct application of the translational approach. As an example of how research can be optimally organized, Dr. Bast focuses on advances being made through the Moon Shots for treatments for breast cancer and ovarian cancer. He also explains that the patients involved in the Moon Shots trials are providing tissue for the study of nine different diseases. Dr. Bast notes that his own work on the mechanisms of autophagy in ovarian cancer (see Session One) connects to this Moon Shot.https://openworks.mdanderson.org/mchv_interviewchapters/1446/thumbnail.jp