Epidemic infectious diseases like HIV/AIDS, tuberculosis, Ebola, and more recently COVID-19, have persistent and devastating impacts in human populations across the globe. In this Review essay, we consider together the monographs Epidemic Illusions (Richardson 2021) and Fevers, Feuds, and Diamonds (Farmer 2020), as well as the documentary film Bending the Arc (Davidson and Kos 2017), Together, they demonstrate the history of transnational colonialism, the significance of structural violence as a contributor to global health inequity, and the increasing presence of co-occurring epidemics worldwide, topics which are often absent from discussions of global health systems. These three works discuss epidemics as pathologies of history and s...