The Muir-Torre syndrome (MTS) is an autosomal dominant genodermatosis characterized by the presence of sebaceous gland tumours, with or without keratoacanthomas, associated with visceral malignancies. We describe and characterize two families in which the ample phenotypic variability of MTS was evident. After clinical evaluation, the skin and visceral tumours of one member of a family with 'classic' MTS and one member of a family with a 'peculiar' MTS phenotype without sebaceous lesions, but with only multiple keratoacanthomas, were analysed for microsatellite instability (MSI) and by immunohistochemistry. Tumours of both individuals showed MSI, with a concomitant lack of MSH2 immunostaining in all evaluated skin and visceral lesions; moreo...
Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal-dominant disorder characterized b...
A "cancer predisposing syndrome" later labeled as Hereditary Non-Polyposis Colorectal Cancer (HNPCC)...
Abstract Background Muir–Torre syndrome (MTS), which accounts for a small subset (1–3 %) of Lynch sy...
The Muir-Torre syndrome (MTS) is an autosomal dominant genodermatosis characterized by the presence ...
Muir-Torre syndrome is an autosomal-dominant skin condition of genetic origin, characterised by tumo...
BACKGROUND: The Muir-Torre syndrome (MTS) is an autosomal-dominant genodermatosis characterized by t...
The Muir-Torre syndrome (MTS) is an autosomal dominantly inherited disorder, characterized by viscer...
Background: We investigated the mutational landscape of skin tumors in patients with Muir-Torre Synd...
The clinical, biomolecular and immunohistochemical characterization of sebaceous skin lesions and ke...
Cutaneous sebaceous neoplasms as markers of Muir-Torre syndrome: a diagnostic algorithm Sebaceous gl...
Muir-Torre syndrome (MTS) is a rare autosomal dominant inherited genodermatosis that is considered t...
Abstract Muir-Torre Syndrome is defined by the coexistence of sebaceous skin tumors and internal mal...
Muir-Torre syndrome is a rare, inherited disease predisposing of gastrointestinal and cutaneous tumo...
Muir-Torre syndrome(MTS) is an autosomal dominant genodermatosis first described in 1967 by Muir and...
Muir-Torre syndrome (MTS) is an autosomal dominant disorder characterized by the presence of at leas...
Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal-dominant disorder characterized b...
A "cancer predisposing syndrome" later labeled as Hereditary Non-Polyposis Colorectal Cancer (HNPCC)...
Abstract Background Muir–Torre syndrome (MTS), which accounts for a small subset (1–3 %) of Lynch sy...
The Muir-Torre syndrome (MTS) is an autosomal dominant genodermatosis characterized by the presence ...
Muir-Torre syndrome is an autosomal-dominant skin condition of genetic origin, characterised by tumo...
BACKGROUND: The Muir-Torre syndrome (MTS) is an autosomal-dominant genodermatosis characterized by t...
The Muir-Torre syndrome (MTS) is an autosomal dominantly inherited disorder, characterized by viscer...
Background: We investigated the mutational landscape of skin tumors in patients with Muir-Torre Synd...
The clinical, biomolecular and immunohistochemical characterization of sebaceous skin lesions and ke...
Cutaneous sebaceous neoplasms as markers of Muir-Torre syndrome: a diagnostic algorithm Sebaceous gl...
Muir-Torre syndrome (MTS) is a rare autosomal dominant inherited genodermatosis that is considered t...
Abstract Muir-Torre Syndrome is defined by the coexistence of sebaceous skin tumors and internal mal...
Muir-Torre syndrome is a rare, inherited disease predisposing of gastrointestinal and cutaneous tumo...
Muir-Torre syndrome(MTS) is an autosomal dominant genodermatosis first described in 1967 by Muir and...
Muir-Torre syndrome (MTS) is an autosomal dominant disorder characterized by the presence of at leas...
Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal-dominant disorder characterized b...
A "cancer predisposing syndrome" later labeled as Hereditary Non-Polyposis Colorectal Cancer (HNPCC)...
Abstract Background Muir–Torre syndrome (MTS), which accounts for a small subset (1–3 %) of Lynch sy...