Add to ORKGBackground: Hepatic stellate cells, the main mediators in the pathogenesis of fibrosis, are triggered by free radicals and produce collagen. Melatonin is a powerful physiologic scavenger of hydroxyl radicals. It is also involved in the inhibitory regulation of the collagen content in tissue. There is no effective treatment available for liver fibrosis. Our objective was to evaluate the effects of melatonin on liver fibrosis induced by bile-duct ligation (BDL) in rats
Nonalcoholic steatohepatitis (NASH) may progress to advanced fibrosis and cirrhosis. Mainly, oxidati...
Melatonin therapy or prolonged exposure to complete darkness reduces biliary hyperplasia and liver f...
Liver fibrosis is scar tissue resulting from an uncontrolled wound-healing process in response to ch...
Increased deposition of the extracellular matrix components, particularly collagen, is a central phe...
The goal of this study was to evaluate the possible protective effects of melatonin against cholesta...
Bile duct ligation (BDL)-treated rats display cholestasis and liver damages. The potential protectiv...
Therapeutic effects of melatonin (MEL) in targeting CCl4-induced liver fibrosis has been widely know...
The objective was to assess the antioxidant effect of melatonin (MLT) on liver and lung tissues of a...
The aim of this study was to assess the effect of melatonin and acetylsalicylic acid (ASA) on hepati...
[EN] Hepatic fibrosis is a reversible response to either acute or chronic cellular injury froma wide...
Abstract: Pineal-gland-derived melatonin (N-Acetyl 5-Methoxytryptamine), which is a known antioxidan...
Primary sclerosing cholangitis (PSC) is characterized by biliary senescence and hepatic fibrosis. Me...
Liver injuries and diseases are serious health problems worldwide. Various factors, such as chemical...
Melatonin, a neuroendocrine hormone synthesized by the pineal gland and cholangiocytes, decreases bi...
Dysregulation of the circadian clock machinery is a critical mechanism in the pathogenesis of fibros...
Nonalcoholic steatohepatitis (NASH) may progress to advanced fibrosis and cirrhosis. Mainly, oxidati...
Melatonin therapy or prolonged exposure to complete darkness reduces biliary hyperplasia and liver f...
Liver fibrosis is scar tissue resulting from an uncontrolled wound-healing process in response to ch...
Increased deposition of the extracellular matrix components, particularly collagen, is a central phe...
The goal of this study was to evaluate the possible protective effects of melatonin against cholesta...
Bile duct ligation (BDL)-treated rats display cholestasis and liver damages. The potential protectiv...
Therapeutic effects of melatonin (MEL) in targeting CCl4-induced liver fibrosis has been widely know...
The objective was to assess the antioxidant effect of melatonin (MLT) on liver and lung tissues of a...
The aim of this study was to assess the effect of melatonin and acetylsalicylic acid (ASA) on hepati...
[EN] Hepatic fibrosis is a reversible response to either acute or chronic cellular injury froma wide...
Abstract: Pineal-gland-derived melatonin (N-Acetyl 5-Methoxytryptamine), which is a known antioxidan...
Primary sclerosing cholangitis (PSC) is characterized by biliary senescence and hepatic fibrosis. Me...
Liver injuries and diseases are serious health problems worldwide. Various factors, such as chemical...
Melatonin, a neuroendocrine hormone synthesized by the pineal gland and cholangiocytes, decreases bi...
Dysregulation of the circadian clock machinery is a critical mechanism in the pathogenesis of fibros...
Nonalcoholic steatohepatitis (NASH) may progress to advanced fibrosis and cirrhosis. Mainly, oxidati...
Melatonin therapy or prolonged exposure to complete darkness reduces biliary hyperplasia and liver f...
Liver fibrosis is scar tissue resulting from an uncontrolled wound-healing process in response to ch...