Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis
- Koyuturk, M
- Fraser, SP
- Diss, JKJ
- Chioni, AM
- Mycielska, ME
- Pan, HY
- Yamaci, RF
- Djamgoz, MBA
- Pani, F
- Siwy, Z
- Krasowska, M
- Grzywna, Z
- Brackenbury, WJ
- Theodorou, D
- Kaya, H
- Battaloglu, E
- De Bella, MT
- Slade, MJ
- Tolhurst, R
- Palmieri, C
- Jiang, J
- Latchman, DS
- Coombes, RC
Publication date
January 2005
DOI Publisher
American Association for Cancer Research (AACR) Journal
Clinical Cancer ResearchAbstract
Purpose: Ion channel activity is involved in several basic cellular behaviors that are integral to metastasis (e.g., proliferation, motility, secretion, and invasion), although their contribution to cancer progression has largely been ignored. The purpose of this study was to investigate voltage-gated Na(+) channel (VGSC) expression and its possible role in human breast cancer
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