Relationship between growth inhibition and mitochondrial function in petite-negative yeasts. II Effects of central nervous system drugs upon pathogenic and non- pathogenic Candida species.
- MARMIROLI N
- TEDESCHI F
- TRUZZI G
- FERRARI C
- PUGLISI P. P.
- SABATINI, Maria Agnese
Publication date
January 1985
DOI Publisher
-PORTLAND PRESS LTD, 59 PORTLAND PLACE, LONDON, ENGLAND, W1B 1QW -Elsevier BV:PO Box 211, 1000 AE Amsterdam Netherlands:011 31 20 4853757, 011 31 20 4853642, 011 31 20 4853641, EMAIL: nlinfo-f@elsevier.nl, INTERNET: http://www.elsevier.nl, Fax: 011 31 20 4853598 ISSN
0248-4900Abstract
Six nervous system drugs which inhibited vegetative reproduction of Saccharomyces cerevisiae arrested also mitotic division of Candida utilis, C. albicans and C. tropicalis. Chlorpromazine and chlorpheniramine which proved to be the most effective, affected respiration and cytochrome biosynthesis. Electrophoretic bands with MW 100K were faint in silver-stained electrophoregrams of proteins from cells grown in the presence of a sub-inhibitory concentration of chlorpromazine
Add to ORKG