Copeptin Does Not Add Diagnostic Information to High-Sensitivity Troponin T in Low- to Intermediate-Risk Patients with Acute Chest Pain: Results from the Rule Out Myocardial Infarction by Computed Tomography (ROMICAT) Study
- Januzzi, James L.
- Koenig, Wolfgang
- Hoffmann, Udo
- Dasdemir, Selçuk
- Bamberg, Fabian
- Rottbauer, Wolfgang
- Truong, Quynh A.
- Schlett, Christopher L.
- Lee, Hang
- Meyer, Julia
- Karakas, Mahir
Publication date
January 2011
DOI Publisher
American Association for Clinical Chemistry (AACC) Journal
Clinical ChemistryAbstract
PURPOSE: Copeptin, a stable peptide derived from the AVP precursor, has been linked to presence and severity of myocardial ischemia. We sought to evaluate the predictive value of copeptin and its incremental value beyond that of high-sensitivity cardiac troponin T (hs-cTnT) in patients with acute chest pain and low to intermediate risk for acute coronary syndrome (ACS)
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