Add to ORKGThe invention provides novel non-/9-lactam inhibitors of ^-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (I) which is set forth in the specification. These compounds may be used with /Mactam antibiotics to treat /J-lactam-antibiotic-resistant bacterial infections. Finally, the invention provides a pharmaceutical composition comprising these compounds
The widespread use of beta-lactam antibiotics has lead to the worldwide appearance of drug-resistant...
In response to the widespread use of beta-lactam antibiotics bacteria have evolved drug resistance m...
β-Lactamases (BLs) are among the main responsible of the threatening spread of Gram- negative pathog...
The invention provides novel non-/9-lactam inhibitors of ^-lactamases. In particular, the invention ...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
he invention relates to novel boronic acid compounds, a method for the preparation of such compounds...
With the aim of improving the ability of non-p-lactam inhibitors to inhibit AmpC-beta-tactamase, a s...
Disclosed herein inter alia are Boron containing compounds and methods for treating infections relat...
The invention provides a method of treating a .beta.-lactam-antibiotic-resistant bacterial infection...
PCT Int. Appl. (2000), 41 pp. CODEN: PIXXD2 WO 0035904 A1 20000622 CAN 133:53675 AN 2000:421...
Provided herein are heterocyclic compounds and pharmaceutical formulations that can be used to treat...
Recent decades have witnessed a dramatic increase of multidrug resistant (MDR) bacteria, compromisin...
The widespread use of beta-lactam antibiotics has lead to the worldwide appearance of drug-resistant...
In response to the widespread use of beta-lactam antibiotics bacteria have evolved drug resistance m...
β-Lactamases (BLs) are among the main responsible of the threatening spread of Gram- negative pathog...
The invention provides novel non-/9-lactam inhibitors of ^-lactamases. In particular, the invention ...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
he invention relates to novel boronic acid compounds, a method for the preparation of such compounds...
With the aim of improving the ability of non-p-lactam inhibitors to inhibit AmpC-beta-tactamase, a s...
Disclosed herein inter alia are Boron containing compounds and methods for treating infections relat...
The invention provides a method of treating a .beta.-lactam-antibiotic-resistant bacterial infection...
PCT Int. Appl. (2000), 41 pp. CODEN: PIXXD2 WO 0035904 A1 20000622 CAN 133:53675 AN 2000:421...
Provided herein are heterocyclic compounds and pharmaceutical formulations that can be used to treat...
Recent decades have witnessed a dramatic increase of multidrug resistant (MDR) bacteria, compromisin...
The widespread use of beta-lactam antibiotics has lead to the worldwide appearance of drug-resistant...
In response to the widespread use of beta-lactam antibiotics bacteria have evolved drug resistance m...
β-Lactamases (BLs) are among the main responsible of the threatening spread of Gram- negative pathog...