Add to ORKGThe invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the specification. These compounds may be used with $g(b)-lactam antibiotics to treat $g(b)-lactam-antibiotic-resistant bacterial infections. Finally, the invention provides a pharmaceutical composition comprising these compound
The widespread use of beta-lactam antibiotics has lead to the worldwide appearance of drug-resistant...
β-Lactamases (BLs) are among the main responsible of the threatening spread of Gram- negative pathog...
The invention relates to heterosubstituted N-thiolated beta-lactams, compositions comprising these c...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
The invention provides novel non-/9-lactam inhibitors of ^-lactamases. In particular, the invention ...
Disclosed herein inter alia are Boron containing compounds and methods for treating infections relat...
he invention relates to novel boronic acid compounds, a method for the preparation of such compounds...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
With the aim of improving the ability of non-p-lactam inhibitors to inhibit AmpC-beta-tactamase, a s...
\u3b2-Lactamase-mediated resistance to \u3b2-lactam antibiotics threatens our antibiotic armamentari...
Bacterial expression of -lactamases is the most widespread resistance mechanism to -lactam antibio...
The invention provides a method of treating a .beta.-lactam-antibiotic-resistant bacterial infection...
Production of β-lactamases (BLs) is the most widespread resistance mechanism adopted by bacteria to ...
The widespread use of beta-lactam antibiotics has lead to the worldwide appearance of drug-resistant...
β-Lactamases (BLs) are among the main responsible of the threatening spread of Gram- negative pathog...
The invention relates to heterosubstituted N-thiolated beta-lactams, compositions comprising these c...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the inv...
The invention provides novel non-/9-lactam inhibitors of ^-lactamases. In particular, the invention ...
Disclosed herein inter alia are Boron containing compounds and methods for treating infections relat...
he invention relates to novel boronic acid compounds, a method for the preparation of such compounds...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
Non-β-lactam inhibitors of β-lactamases are provided. In particular, the invention provides such in...
With the aim of improving the ability of non-p-lactam inhibitors to inhibit AmpC-beta-tactamase, a s...
\u3b2-Lactamase-mediated resistance to \u3b2-lactam antibiotics threatens our antibiotic armamentari...
Bacterial expression of -lactamases is the most widespread resistance mechanism to -lactam antibio...
The invention provides a method of treating a .beta.-lactam-antibiotic-resistant bacterial infection...
Production of β-lactamases (BLs) is the most widespread resistance mechanism adopted by bacteria to ...
The widespread use of beta-lactam antibiotics has lead to the worldwide appearance of drug-resistant...
β-Lactamases (BLs) are among the main responsible of the threatening spread of Gram- negative pathog...
The invention relates to heterosubstituted N-thiolated beta-lactams, compositions comprising these c...