Add to ORKGThe same FLT3-internal tandem duplication (ITD) positive clone was detected at diagnosis and relapse, but not at birth, in a child with M1 acute myeloid leukemia. Single nucleotide polymorphism arrays demonstrated that chromosome 13 acquired uniparental disomy, in association with del(9q), represented a progressive event in the course of the disease, and it was responsible for the homozygous FLT3-ITD at relapse
An 18-month-old girl was diagnosed with prepre-B ALL/t(4;11) leukemia, which during thetreatment and...
Loss of heterozygosity (LOH) is detectable in many forms of cancer including leukaemia. It contribut...
Item does not contain fulltextMixed-lineage leukaemia (MLL)-partial tandem duplications (PTDs) are f...
The same FLT3-internal tandem duplication (ITD) positive clone was detected at diagnosis and relapse...
PhDInvestigation of the genetics of acute myeloid leukaemia (AML) has revealed the underlying basis...
Despite advances in the curative treatment of acute myeloid leukemia (AML), recurrence will occur in...
FLT3 internal tandem duplication (ITD), one of the most frequent mutations in Acute Myeloid Leukemia...
A recurrent somatic mutation frequently found in cytogenetically normal acute myeloid leukemia (AML)...
Acute myeloid leukemia (AML) patients with fms-related tyrosine kinase 3 (FLT3)-internal tandem dupl...
Background and purpose: Mutation of FMS like tyrosine kinase (flt3) gene causes uncontrolled prolife...
In acute myeloid leukaemia (AML), further prognostic determinants are required in addition to cytoge...
Abstract Background and purpose: Mutation of FMS like tyrosine kinase (flt3) gene causes uncontrol...
Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AM...
We report a case of de novo acute myeloid leukemia (AML) with unstable FLT3 gene mutations and stabl...
Abstract Juvenile myelomonocytic leukemia (JMML) is a rare myeloproliferative disease of early child...
An 18-month-old girl was diagnosed with prepre-B ALL/t(4;11) leukemia, which during thetreatment and...
Loss of heterozygosity (LOH) is detectable in many forms of cancer including leukaemia. It contribut...
Item does not contain fulltextMixed-lineage leukaemia (MLL)-partial tandem duplications (PTDs) are f...
The same FLT3-internal tandem duplication (ITD) positive clone was detected at diagnosis and relapse...
PhDInvestigation of the genetics of acute myeloid leukaemia (AML) has revealed the underlying basis...
Despite advances in the curative treatment of acute myeloid leukemia (AML), recurrence will occur in...
FLT3 internal tandem duplication (ITD), one of the most frequent mutations in Acute Myeloid Leukemia...
A recurrent somatic mutation frequently found in cytogenetically normal acute myeloid leukemia (AML)...
Acute myeloid leukemia (AML) patients with fms-related tyrosine kinase 3 (FLT3)-internal tandem dupl...
Background and purpose: Mutation of FMS like tyrosine kinase (flt3) gene causes uncontrolled prolife...
In acute myeloid leukaemia (AML), further prognostic determinants are required in addition to cytoge...
Abstract Background and purpose: Mutation of FMS like tyrosine kinase (flt3) gene causes uncontrol...
Copy-neutral loss of heterozygosity is prevalent and a late event in the pathogenesis of FLT3/ITD AM...
We report a case of de novo acute myeloid leukemia (AML) with unstable FLT3 gene mutations and stabl...
Abstract Juvenile myelomonocytic leukemia (JMML) is a rare myeloproliferative disease of early child...
An 18-month-old girl was diagnosed with prepre-B ALL/t(4;11) leukemia, which during thetreatment and...
Loss of heterozygosity (LOH) is detectable in many forms of cancer including leukaemia. It contribut...
Item does not contain fulltextMixed-lineage leukaemia (MLL)-partial tandem duplications (PTDs) are f...