Scope: Chlorogenic acid (3-O-caffeoyl-quinic acid, C-QA), the caffeic ester of quinic acid, is one of the most abundant phenolic acids in Western diet. The majority of C-QA escapes absorption in the small intestine and reaches the colon, where the resident microbiota transforms it into several metabolites. C-QA conversion by the gut microbiota from nine subjects was compared to evaluate the variability of bacterial metabolism. It was investigated whether a potentially probiotic Bifidobacterium strain, capable of C-QA hydrolysis, could affect C-QA fate. Methods and results: Bioconversion experiments exploiting the microbiota from diverse subjects revealed that C-QA was metabolized through a succession of hydrogenation, dexydroxylation and es...
Free hydroxycinnamates, including caffeic, ferulic and p-coumaric acids, exhibit antioxidant and ant...
Scope: Coffee is rich in quinic acid esters of phenolic acids (chlorogenic acids) but also contains ...
International audienceThe absorption and metabolism in the small intestine of chlorogenic acid (5-O-...
Scope: Chlorogenic acid (3-O-caffeoyl-quinic acid, C-QA), the caffeic ester of quinic acid, is one o...
Scope: Quinic acid in its free form is broadly abundant in plants, and can accumulate in copious amo...
Caffeic acid and its esters, chlorogenic and caftaric acids, are major dietary polyphenols present i...
It has been believed that the metabolism of xenobiotics occurred mainly by the cytochrome P450 enzym...
International audienceMicrobiota is known to play a pivotal role in generating bioavailable and bioa...
This study aimed to explore the capability of potentially probiotic bifidobacteria to hydrolyze chlo...
Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee; ...
Coffee is a relatively rich source of chlorogenic acids (CGA), which, like other polyphenols are pos...
Several studies have indicated potential health benefits associated with coffee consumption. These b...
There are numerous species of bacteria resides in the lumen of human colon. The word ‘colon’, resemb...
International audienceAim: Polyphenols, dietary compounds, have drawn increasing attention due to th...
More and more evidence show that the trillions of bacteria housed in the gastro-intestinal tract, an...
Free hydroxycinnamates, including caffeic, ferulic and p-coumaric acids, exhibit antioxidant and ant...
Scope: Coffee is rich in quinic acid esters of phenolic acids (chlorogenic acids) but also contains ...
International audienceThe absorption and metabolism in the small intestine of chlorogenic acid (5-O-...
Scope: Chlorogenic acid (3-O-caffeoyl-quinic acid, C-QA), the caffeic ester of quinic acid, is one o...
Scope: Quinic acid in its free form is broadly abundant in plants, and can accumulate in copious amo...
Caffeic acid and its esters, chlorogenic and caftaric acids, are major dietary polyphenols present i...
It has been believed that the metabolism of xenobiotics occurred mainly by the cytochrome P450 enzym...
International audienceMicrobiota is known to play a pivotal role in generating bioavailable and bioa...
This study aimed to explore the capability of potentially probiotic bifidobacteria to hydrolyze chlo...
Chlorogenic acid, an ester of caffeic acid and quinic acid, is a major phenolic compound in coffee; ...
Coffee is a relatively rich source of chlorogenic acids (CGA), which, like other polyphenols are pos...
Several studies have indicated potential health benefits associated with coffee consumption. These b...
There are numerous species of bacteria resides in the lumen of human colon. The word ‘colon’, resemb...
International audienceAim: Polyphenols, dietary compounds, have drawn increasing attention due to th...
More and more evidence show that the trillions of bacteria housed in the gastro-intestinal tract, an...
Free hydroxycinnamates, including caffeic, ferulic and p-coumaric acids, exhibit antioxidant and ant...
Scope: Coffee is rich in quinic acid esters of phenolic acids (chlorogenic acids) but also contains ...
International audienceThe absorption and metabolism in the small intestine of chlorogenic acid (5-O-...