We used concentrations of in situ cosmogenic10Be from riverine sediment to quantify the basin‐averaged denudation rates and sediment fluxes in the Plessur Basin, Eastern Swiss Alps, which is a tributary stream to the Alpine Rhine, one of the largest streams in Europe. We complement the cosmogenic dataset with the results of morphometric analyses, geomorphic mapping, and sediment fingerprinting techniques. The results reveal that the Plessur Basin is still adjusting to the landscape perturbation caused by the glacial carving during the Last Glacial Maximum c. 20,000 years ago. This adjustment has been most efficient in the downstream part where the bedrock comprises high erodibility North Penninic flysch and Bündnerschist, whereas glacial la...