Global incidence of oral and oropharynx cancer in patients younger than 45 years versus older patients: A systematic review
- Hussein, A.A.
- Helder, M.N.
- de Visscher, J.G.
- Leemans, C.R.
- Braakhuis, B.J.
- de Vet, H.C.W.
- Forouzanfar, T.
DOIAbstract
Head and neck squamous cell carcinoma (HNSCC) is typically regarded as a disease of elderly people. However, increasing numbers of patients worldwide with HNSCC at younger age (defined as <45 years old) have been reported in recent years. To assess geographical variations and trends worldwide in incidence of oral and oropharyngeal cancer in young patients, a systematic review was conducted in PubMed and Google scholar databases from 1975 to June 2016. Seventy-eight studies were selected for further study. Nineteen population-based studies on incidence rate were available from 13 countries, showing a prominent increase over time except for the Netherlands. A notable rise of oral (mobile) tongue cancer among white women and oropharyngeal canc...
Add to ORKG